Results 61 to 70 of about 10,536,235 (262)

Preventative Effect of a Flavonoid, Enzymatically Modified Isoquercitrin on Ocular Symptoms of Japanese Cedar Pollinosis

Allergology International, 2009
Background: Flavonoids are nutrients that exert anti-allergic effects. We investigated the preventative effect of enzymatically modified isoquercitrin (EMIQ), a flavonoid, to relieve the symptoms of Japanese cedar pollinosis. Methods: In a parallel-group,
Toru Hirano, Mari Kawai, Junsuke Arimitsu, Masako Ogawa, Yusuke Kuwahara, Keisuke Hagihara, Yoshihito Shima, Masashi Narazaki, Atsushi Ogata, Mihoko Koyanagi, Tomoko Kai, Ryosuke Shimizu, Masamitsu Moriwaki, Yukio Suzuki, Satoshi Ogino, Ichiro Kawase, Toshio Tanaka   +16 more
doaj   +1 more source

Role of Nigella sativa in the Management of Osteoarthritis: A Systematic Review

Traditional and Integrative Medicine, 2023
Because of the anti-inflammatory properties of thymoquinone (TQ), as the main bioactive substance of Nigella sativa, this systematic review aimed at assessing the therapeutic effects of N.
Mozhdeh Ghamari, Masoumeh Salari, Mandana Khodashahi   +2 more
doaj   +1 more source

Impact of disease modifying anti-rheumatic drugs on vaccine immunogenicity in patients with inflammatory rheumatic and musculoskeletal diseases

Annals of the Rheumatic Diseases, 2021
Patients with rheumatic diseases are at increased risk of infectious complications; vaccinations are a critical component of their care. Disease-modifying antirheumatic drugs may reduce the immunogenicity of common vaccines. We will review here available
M. Friedman, J. Curtis, K. Winthrop
semanticscholar   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Serum B cell activating factor (BAFF) and sarcoidosis activity

The Turkish Journal of Gastroenterology, 2021
Objectives: This study aims to determine the relationship between the severity of sarcoidosis and serum B-cell activating factor (BAFF) concentrations.
Kamila HASHEMZADEH, Maryam FATEMIPOUR, Seyede ZAHRA MIRFEIZI, Mohammadhasan JOKAR, Zhaleh SHARIATI SARABI, Mohammad-Reza HATEF FARD, Houshang RAFATPANAH, Mandana KHODASHAHI   +7 more
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis

Arthritis Research & Therapy, 2018
Background IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony ankylosis.
Sungsin Jo, Sung Eun Wang, Young Lim Lee, Suman Kang, Bitnara Lee, Jinil Han, Il-Hoon Sung, Ye-Soo Park, Sang-Cheol Bae, Tae-Hwan Kim   +9 more
doaj   +1 more source

The Role of Extracellular Matrix and Hydrogels in Mesenchymal Stem Cell Chondrogenesis and Cartilage Regeneration

Life, 2022
Diseases associated with articular cartilage disintegration or loss are still therapeutically challenging. The traditional treatment approaches only alleviate the symptoms while potentially causing serious side effects. The limited self-renewal potential
Magdalena Strecanska, Lubos Danisovic, Stanislav Ziaran, Michaela Cehakova   +3 more
doaj   +1 more source

Experiences of Patients With Rheumatic Diseases in the United States During Early Days of the COVID‐19 Pandemic

ACR Open Rheumatology, 2020
Patients with rheumatic diseases such as rheumatoid arthritis (RA) and lupus have increased risk of infection and are treated with medications that may increase this risk yet are also hypothesized to help treat COVID‐19.
K. Michaud, K. Wipfler, Y. Shaw, T. Simon, Adam S. Cornish, B. England, A. Ogdie, P. Katz   +7 more
semanticscholar   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source