Results 51 to 60 of about 10,536,235 (262)

Glycosylation and rheumatic disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1998
Rheumatoid arthritis (RA) and other rheumatic diseases are associated with a significant defect in the galactosyltransferase enzyme that results in a profound change in the galactosylation of immunoglobulin G. This change has been demonstrated to be integrally associated with pathogenic mechanisms associated with inflammation in RA.
openaire   +3 more sources

The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases

Annals of Laboratory Medicine, 2019
The platelet-to-lymphocyte ratio (PLR) has emerged as an informative marker revealing shifts in platelet and lymphocyte counts due to acute inflammatory and prothrombotic states.
A. Gasparyan, L. Ayvazyan, Ulzhan Mukanova, M. Yessirkepov, G. Kitas   +4 more
semanticscholar   +1 more source

Adjunct role of potassium-rich vegetarian diet and a novel potassium food supplement to improve pain in chronic rheumatoid arthritis on supervised standard care: a randomised controlled study

BMJ Nutrition, Prevention & Health
Introduction An earlier food survey showed dietary potassium deficiency in rheumatoid arthritis (RA).Objective To evaluate an adjunct role of oral potassium to reduce joint pain in RA.Methods 172 consenting eligible symptomatic patients (median duration ...
Arvind Chopra, Manjit Saluja, Toktam Kianifard, Sanjeev Sarmukaddam, Anuradha Venugopalan   +4 more
doaj   +1 more source

Associations between cardiovascular risk factors, disease activity and cardiorespiratory fitness in patients with inflammatory joint disease: a cross-sectional analysis

BMC Sports Science, Medicine and Rehabilitation, 2023
Background Inflammatory joint diseases (IJD) are accompanied by an increased risk of cardiovascular disease (CVD). Cardiorespiratory fitness (CRF) is a modifiable CVD risk factor and low levels of CRF associate with an elevated CVD risk. This study aimed
Kristine Røren Nordén, Anne Grete Semb, Hanne Dagfinrud, Jonny Hisdal, Sigrid Ødegård, Joseph Sexton, Camilla Fongen, Jon Skandsen, Thalita Blanck, George S. Metsios, Anne Therese Tveter   +10 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Epigentics in rheumatic diseases

Zeitschrift fur Rheumatologie, 2011
The human genome comprises approximately 30000 genes needed for the formation and function of approximately 1 Million proteins in the human body. Differentiation leads to the deactivation of genes that are not needed in the specific tissues or cells. To regulate the cell specific gene expression in normal cells epigenetic modifications work in concert ...
Jüngel, A, Gay, S
openaire   +4 more sources

Photosensitivity in Rheumatic Diseases [PDF]

Journal of Investigative Dermatology Symposium Proceedings, 2004
There have been a number of recent advances in the genetic understanding of photosensitive rheumatic diseases, especially subacute cutaneous lupus erythematosus and dermatomyositis. These advances support the concept that increased numbers of ultraviolet light-induced apoptotic cells in skin lead to a supra-threshold concentration of antigenic peptides.
Werth, Victoria P., Bashir, Muhammad, Zhang, Wei   +2 more
openaire   +2 more sources

Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study

Annals of the Rheumatic Diseases, 2020
Objectives The impact of inflammatory rheumatic diseases on COVID-19 severity is poorly known. Here, we compare the outcomes of a cohort of patients with rheumatic diseases with a matched control cohort to identify potential risk factors for severe ...
J. Pablos, M. Galindo, L. Carmona, A. Lledó, M. Retuerto, R. Blanco, M. González-Gay, D. Martínez-López, Isabel Castrejón, J. Álvaro-Gracia, D. Fernández Fernández, A. Mera-Varela, S. Manrique-Arija, Natalia Mena Vázquez, A. Fernández-Nebro   +14 more
semanticscholar   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source