Results 81 to 90 of about 268,778 (321)

Introduction [PDF]

open access: yes, 1974
The 45th Annual McGuire Lecture Series has been devoted to the subject of Immunology and the Rheumatic Diseases. In this two-day period, 22 outstanding physicians in the field of immunology and rheumatology brought an up-to-date overall concept in the ...
Irby, Robert
core   +1 more source

Slum health: diseases of neglected populations. [PDF]

open access: yes, 2007
BackgroundUrban slums, like refugee communities, comprise a social cluster that engenders a distinct set of health problems. With 1 billion people currently estimated to live in such communities, this neglected population has become a major reservoir for
Ko, Albert I   +3 more
core   +2 more sources

Juvenile Idiopathic Arthritis, Earnings, and Work Loss: A Nationwide Matched Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study compares trajectories of earnings and work loss in individuals with juvenile idiopathic arthritis (JIA) versus matched comparators from the general population. Methods Patients with JIA (n = 4,737) were identified in the Swedish National Patient Register (2001–2017) and individually matched to up to five general population ...
Heather Miller   +4 more
wiley   +1 more source

A Tracy-Widom Empirical Estimator For Valid P-values With High-Dimensional Datasets [PDF]

open access: yesarXiv, 2018
Recent technological advances in many domains including both genomics and brain imaging have led to an abundance of high-dimensional and correlated data being routinely collected. Classical multivariate approaches like Multivariate Analysis of Variance (MANOVA) and Canonical Correlation Analysis (CCA) can be used to study relationships between such ...
arxiv  

The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]

open access: yes, 2013
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified ...
arxiv   +1 more source

Antibiotics for sore throat [PDF]

open access: yes, 2006
BACKGROUND: Sore throat is a very common reason for people to present for medical care. Although it remits spontaneously, primary care doctors commonly prescribe antibiotics for it.
Barwitz   +78 more
core   +1 more source

Placebo Effect Sizes in Clinical Trials of Knee Osteoarthritis Using Intra‐Articular Injections of Biologic Agents

open access: yesArthritis Care &Research, EarlyView.
Objective Patients with knee osteoarthritis rely on symptomatic treatments, in which up to 75% of the pain reduction can be attributed to the placebo effect. This effect may vary based on treatment type (eg, biologics vs nonbiologic injection) and route of administration (eg, intra‐articular vs topical vs oral).
Johanna M. Borst   +5 more
wiley   +1 more source

Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]

open access: yes, 2015
Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario   +4 more
core   +4 more sources

Diverse Treatment Goals in Psoriatic Arthritis: Insights From Participants in the PARC Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to examine patient‐reported treatment goals among individuals with psoriatic arthritis. Methods Participants in the Psoriatic Arthritis Research Consortium completed standardized assessments, including patient‐reported outcome (PROs) instruments, between 2017 and 2020.
Astia Allenzara   +8 more
wiley   +1 more source

OHMI: The Ontology of Host-Microbiome Interactions [PDF]

open access: yes, 2019
Host-microbiome interactions (HMIs) are critical for the modulation of biological processes and are associated with several diseases, and extensive HMI studies have generated large amounts of data.
Alekseyenko, Alexander V.   +11 more
core  

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