Results 91 to 100 of about 879,459 (400)
Non-valvular atrial fibrillation and stroke : implications for management [PDF]
Nonvalvular Atrial Fibrillation is more prevalent with increasing age. It is associated with a six-fold excess risk of stroke; and a cumulative lifetime stroke risk of 35%. 15% of ischaemic strokes are directly attributable to it.
Tilney, Myra Kay
core
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra+14 more
core +4 more sources
Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh+3 more
wiley +1 more source
BackgroundRheumatic heart disease is a global health concern with a persistently high incidence in developing countries, including Africa. It has a significant economic, morbidity, and mortality burden, particularly for children and young adults during ...
Seid Mohammed Abdu+8 more
doaj +1 more source
Tingkat Disabilitas Fisik Berdasarkan Penyakit Degeneratif yang Diderita Menurut Faktor Sosial dan Demografi (Kajian Isu Publik dalam Formulasi Kebijakan Kesehatan) [PDF]
Background: Riskesdas 2007 showed that 18.4% had been death by stroke; 8.3% by Diabetes Mellitus and hipertension;6.7% by heart. Hipertension is main trigger of stroke attacked and it is caused physical disability.
Astuti, W. D. (Wahyu)+1 more
core
Quantitative sensory testing in painful hand osteoarthritis demonstrates features of peripheral sensitisation. [PDF]
Hand osteoarthritis (HOA) is a prevalent condition for which treatments are based on analgesia and physical therapies. Our primary objective was to evaluate pain perception in participants with HOA by assessing the characteristics of nodal involvement ...
Ejindu, V+5 more
core +2 more sources
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang+9 more
wiley +1 more source
Left atrial anomalous muscular band as incidental finding during video-assisted mitral surgery [PDF]
Congenital fibromuscular bands have been described inleft ventricle or right atrium and have been diagnosed by echocardiography and CT scan. The first report of anomalous band in the left atrium was described in 1897 by Rollestone (1).
Baldascino, Francesco+6 more
core +1 more source
The kidney in rheumatic heart disease [PDF]
Histological evidence of glomerulonephritis is reported in 95 (38.6%) of a series of 246 necropsies with concomitant rheumatic carditis. The details of these findings are given and their significance is discussed.
openaire +3 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source