Results 111 to 120 of about 6,012,951 (335)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

RHD elimination: action needed beyond secondary prophylaxis

Australian and New Zealand Journal of Public Health, 2020
Kate Hardie, Anna P. Ralph, Jessica L. deDassel   +2 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Resurgence of rheumatic fever among Pacific peoples in Aotearoa New Zealand: A 2010–2023 analysis of hospitalisation data with implications for equity policy

Australian and New Zealand Journal of Public Health
Objective: The objective of this study was to assess ethnic, geographic and socioeconomic patterns in acute rheumatic fever and rheumatic heart disease hospitalisations in New Zealand (2010–2023), evaluate the impact of public health interventions and ...
Gerard JB. Sonder, Megan Pledger, Philip C. Hill, Debbie Ryan   +3 more
doaj   +1 more source

The burden of rheumatic heart disease among children in Lagos: how are we faring?

The Pan African Medical Journal, 2018
INTRODUCTION: Rheumatic heart disease still remains a cause of morbidity and mortality in low and middle income countries, despite its eradication in developed societies.
Barakat Adeola Animasahun, Akpoembele Deborah Madise Wobo, Adejumoke Yemisi Itiola, Motunrayo Oluwabukola Adekunle, Olusola Yejide Kusimo, Fidelia Bode Thomas   +5 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Predictors of rheumatic heart disease.

, 2015
Predictors of rheumatic heart disease.
Reto Kurmann (775262), Pedro Torres (775266), Martina Rothenbühler (672060), Fabian Zürcher (775263), Peter Jüni (50488), Fabian Islas (775261), Thomas Pilgrim (339922), Ernest Spitzer (775259), Nassip Llerena (775265), Peter Krähenmann (775264), Jorge Mercado (775260)   +10 more
core   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Better cardiac care measures for Aboriginal and Torres Strait Islander people: first national report 2015 [PDF]

, 2015
Mortality from cardiac conditions for Indigenous Australians decreased by 41% between 1998 and 2012, while access to cardiac care has improved over time.
Australian Institute of Health and Welfare
core  

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source