Results 121 to 130 of about 879,459 (400)

Neglecting the neglected: the objective evidence of underfunding in rheumatic heart disease

open access: yesTransactions of the Royal Society of Tropical Medicine and Hygiene, 2019
Background Despite the substantial global burden of disease, rheumatic heart disease research receives little funding globally. Methods Using data from the Global Burden of Disease Study and funding from the G-FINDER database, we propose a novel ...
C. Macleod   +5 more
semanticscholar   +1 more source

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

open access: yesAdvanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban   +5 more
wiley   +1 more source

Application of Transthoracic Echocardiography for Cardiac Safety Evaluation in the Clinical Development Process of Vaccines Against Streptococcus pyogenes

open access: yesDrugs in R&D
Superficial infections with Streptococcus pyogenes (Strep A), pharyngitis and impetigo can induce acute rheumatic fever, an autoimmune sequela manifesting mostly with arthritis and rheumatic carditis.
Usman Nakakana   +8 more
doaj   +1 more source

Comparison Between Different Strategies of Rheumatic Heart Disease Echocardiographic Screening in Brazil: Data From the PROVAR (Rheumatic Valve Disease Screening Program) Study

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Considering the limited accuracy of clinical examination for early diagnosis of rheumatic heart disease (RHD), echocardiography has emerged as an important epidemiological tool. The ideal setting for screening is yet to be defined. We aimed to
B. Nascimento   +31 more
semanticscholar   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

open access: yesAdvanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai   +6 more
wiley   +1 more source

RELATIONSHIP OF TNF-A-308, IL-10–1082 GENE POLYMORPHISMS WITH THE SEVERITY AND SUSCEPTIBILITY OF RHEUMATIC HEART DISEASE IN TURKISH CHILDREN

open access: yesРоссийский кардиологический журнал, 2014
Aim. Acute rheumatic fever is an inflammatory disease developing after upper respiratory tract infection with group A streptoccoci and its most important complication is rheumatic heart disease (RHD). Tumor necrosis factor (TNF)-α and interleukin (IL) –1–
Hallioglu Olgu   +3 more
doaj   +1 more source

Cardiovascular involvement in Kawaski Disease [PDF]

open access: yes, 2005
This article contains a case report of a 19 month old child with Kawasaki Disease who developed bilateral giant coronary artery aneurysms.peer ...
Chintala, Kavitha   +2 more
core  

Group A Streptococcus, Acute Rheumatic Fever and Rheumatic Heart Disease: Epidemiology and Clinical Considerations

open access: yesCurrent Treatment Options in Cardiovascular Medicine, 2017
Opinion statementEarly recognition of group A streptococcal pharyngitis and appropriate management with benzathine penicillin using local clinical prediction rules together with validated rapi-strep testing when available should be incorporated in ...
L. Zühlke   +12 more
semanticscholar   +1 more source

Designing the Next Generation of Biomaterials through Nanoengineering

open access: yesAdvanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr.   +3 more
wiley   +1 more source

Rheumatic heart disease burden, trends, and inequalities in the Americas, 1990–2017: a population-based study

open access: yesThe Lancet Global Health, 2019
Summary: Background: The World Health Assembly 2018 approved a resolution on rheumatic heart disease to strengthen programmes in countries where this condition remains a substantial public health problem. We aimed to describe the regional burden, trends,
Pedro Ordunez, PhD   +5 more
doaj  

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