Results 161 to 170 of about 879,459 (400)

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

Advanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen   +7 more
wiley   +1 more source

Takayasu's arteritis in children : a review [PDF]

, 2001
Takayasu's arteritis is an inflammatory disease of unknown origin involving aorta, its primary branches and pulmonary artery. This article briefly reviews the pathology, clinical features and treatment of Takayasu's arteritis, focusing mainly on the ...
Kothari, Shyam S.
core   +1 more source

Necropsy study of endomyocardial fibrosis and rheumatic heart disease in Uganda 1950-1965. [PDF]

, 1968
A. G. Shaper, M. S. R. Hutt, Ruth M. Coles   +2 more
openalex   +1 more source

Global, Regional, and National Burden of Rheumatic Heart Disease, 1990–2015

New England Journal of Medicine, 2017
D. Watkins, C. Johnson, Samantha M. Colquhoun, G. Karthikeyan, A. Beaton, G. Bukhman, M. Forouzanfar, C. Longenecker, B. Mayosi, G. Mensah, B. Nascimento, A. Ribeiro, C. Sable, A. Steer, M. Naghavi, A. Mokdad, C. Murray, T. Vos, J. Carapetis, Gregory A. Roth   +19 more
semanticscholar   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Rheumatic Fever and Rheumatic Heart Disease among U.S. College Freshmen, 1956-65: Prevalence, Prophylaxis [PDF]

, 1968
Lowell W. Perry, Jean-Maurice Poitras, Clare Findlan   +2 more
openalex   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Group a streptococcal serotypes isolated from healthy schoolchildren in iran [PDF]

, 2003
Serotypes of group A streptococci are still a major cause of pharyngitis and some post-infectious sequelae such as rheumatic fever. As part of the worldwide effort to clarify the epidemiological pattern of group A streptococci in different countries, the
Fazeli, M.R., Ghaemi, E., Johnson, D.R., Kaplan, E.L., Khodabakhshi, B., Tabarraei, A., Vakili, M.A.   +6 more
core  

INTRACARDIAC ACETYLCHOLINE INFUSION AND LEFT HEART DYNAMICS IN RHEUMATIC HEART DISEASE [PDF]

, 1961
Philip Samet, William H. Bernstein, Robert S. Litwak   +2 more
openalex   +1 more source

Lung‐Penetrating Biomimetic Extracellular Vesicle Spherical Nucleic Acids for Pulmonary Fibrosis Therapy Through ROS Scavenging and Anti‐Inflammatory Effects

Aggregate, EarlyView.
This work describes a biomimetic extracellular vesicle‐spherical nucleic acid (BEV‐SNA) platform for idiopathic pulmonary fibrosis (IPF) therapy. BEV‐SNA is composed of mechanically extruded BEVs from primary MSCs and cholesterol‐modified ssDNA that are assembled through hydrophobic interactions.
Saiyun Lou, Jiangpo Ma, Pan Fu, Lin Li, Jingyun Huang, Fangxue Jing, Yuhui Wang, Sihua Qian, Jianping Zheng, Jiang Li, Zhaoxing Dong, Kaizhe Wang   +11 more
wiley   +1 more source