Results 71 to 80 of about 87,039 (290)
A Tracy-Widom Empirical Estimator For Valid P-values With High-Dimensional Datasets [PDF]
arXiv, 2018 Recent technological advances in many domains including both genomics and brain imaging have led to an abundance of high-dimensional and correlated data being routinely collected. Classical multivariate approaches like Multivariate Analysis of Variance (MANOVA) and Canonical Correlation Analysis (CCA) can be used to study relationships between such ...
arxiv
Advanced Science, EarlyView.Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang +11 more
wiley +1 more source
Autopsy and Case Reports, 2021 Rheumatic heart disease is still common in developing countries and requires prompt intervention to prevent chronic complications. Vegetations in rheumatic heart disease might be due to acute episodes of rheumatic fever itself or due to either infective ...
Aravind Sekar, Sanjeev Naganur
doaj
INFECTIVE ENDOCARDITIS IN A RHEUMATOLOGIST'S PRACTICE
Научно-практическая ревматология, 2012 Objective: to analyze «rheumatic» symptoms in patients with infective endocarditis (IE) and to investigate the specific features of the disease and hemodynamics in patients with prior rheumatic valvular disease Subjects and methods.
E Yu Ponomareva, Andrei Petrovich Rebrov
doaj +1 more source
Advanced Science, EarlyView.The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang +6 more
wiley +1 more source
The kidney in rheumatic heart disease [PDF]
Journal of Clinical Pathology, 1962 Histological evidence of glomerulonephritis is reported in 95 (38.6%) of a series of 246 necropsies with concomitant rheumatic carditis. The details of these findings are given and their significance is discussed.
openaire +3 more sources
Advanced Science, EarlyView.Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang +9 more
wiley +1 more source
Rheumatic fever and rheumatic heart disease in Africa
South African Medical Journal, 2015 No Abstract.
openaire +6 more sources
Advanced Science, EarlyView.This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv +8 more
wiley +1 more source
Advanced Science, EarlyView.CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu +14 more
wiley +1 more source