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The genetic basis for the inverse relationship between rheumatoid arthritis and schizophrenia

Molecular Genetics & Genomic Medicine, 2020
Introduction Rheumatoid arthritis is a common autoimmune disease and schizophrenia is a relatively common and debilitating neurological disorder. There are several common features between rheumatoid arthritis and schizophrenia.
Mansour Zamanpoor, Hamid Ghaedi, Mir Davood Omrani   +2 more
doaj   +1 more source

Comparison of the Belgian Rheumatoid Arthritis Disability Assessment and Health Assessment Questionnaires as Tools to Predict the Need for Support Measures in Patients with Rheumatoid Arthritis. [PDF]

PLoS ONE, 2016
OBJECTIVE:Scores on the Health Assessment Questionnaire (HAQ) predict the need for support measures in patients with rheumatoid arthritis (RA). In this study we compare the performance of the HAQ in this context with that of the more disease-specific ...
Xavier Janssens, Saskia Decuman, Filip De Keyser, Belgian Rheumatoid Arthritis Disability Assessment study group   +3 more
doaj   +1 more source

Rheumatoid meningitis sine arthritis. [PDF]

, 2018
Rheumatoid meningitis is a rare and very serious extra-articular manifestation of rheumatoid arthritis. We present a case of a 7()year-old female with no history of arthritis who developed stroke-like symptoms, seizures, psychosis and compulsive behavior.
Berk, Matthew, Kenyon, Lawrence C., Lee-Ching, Cathy, Park, Chantel   +3 more
core   +1 more source

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

Nature Communications, 2018
Fibroblasts regulate tissue homeostasis, coordinate inflammatory responses, and mediate tissue damage. In rheumatoid arthritis (RA), synovial fibroblasts maintain chronic inflammation which leads to joint destruction.
F. Mizoguchi, Kamil Slowikowski, Kevin Wei, J. Marshall, Deepak A. Rao, S. Chang, Hung N. Nguyen, E. Noss, J. Turner, Brandon E. Earp, P. Blazar, John Wright, B. Simmons, L. Donlin, G. Kalliolias, S. Goodman, V. Bykerk, L. Ivashkiv, J. Lederer, N. Hacohen, P. Nigrovic, A. Filer, C. Buckley, S. Raychaudhuri, M. Brenner   +24 more
semanticscholar   +1 more source

Rheumatoid arthritis

Current Opinion in Immunology, 1992
Rheumatoid arthritis is often considered to be an autoimmune disease in which the abnormal immunological response is triggered by an infectious agent(s) but progress towards identifying such extrinsic factors has so far been unrevealing. In contrast, the genetic component of host susceptibility is slowly becoming clearer.
openaire   +2 more sources

Effects of Non‐Aspirin Nonsteroidal Anti‐Inflammatory Drugs on Acute Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite celecoxib, a cyclooxygenase‐2 inhibitor, promoting functional recovery from intracerebral hemorrhage (ICH) by reducing inflammation‐mediated perihematomal edema in rat models, the evidence of its effects on patient outcomes remains limited.
Shin‐Joe Yeh, Sung‐Chun Tang, Li‐Kai Tsai, Jiann‐Shing Jeng   +3 more
wiley   +1 more source

Diagnosis and activity prediction of SLE based on serum Raman spectroscopy combined with a two-branch Bayesian network

Frontiers in Immunology
ObjectiveThis study aims to examine the impact of systemic lupus erythematosus (SLE) on various organs and tissues throughout the body. SLE is a chronic autoimmune disease that, if left untreated, can lead to irreversible damage to these organs.
Qianxi Xu, Qianxi Xu, Qianxi Xu, Xue Wu, Xue Wu, Xue Wu, Xinya Chen, Ziyang Zhang, Jinrun Wang, Jinrun Wang, Zhengfang Li, Zhengfang Li, Zhengfang Li, Xiaomei Chen, Xiaomei Chen, Xiaomei Chen, Xin Lei, Xin Lei, Zhuoyu Li, Zhuoyu Li, Zhuoyu Li, Mengsi Ma, Mengsi Ma, Mengsi Ma, Chen Chen, Lijun Wu, Lijun Wu   +26 more
doaj   +1 more source

Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study [PDF]

, 2005
Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability.
Bukulmez, H, Colbert, RA, Elston, RC, Fife, M, Glass, DN, Olson, JM, Thompson, SD, Tsoras, M, Twine, NA, Woo, P   +9 more
core   +2 more sources

Rheumatoid Arthritis: A Brief Overview of the Treatment

Medical Principles and Practice, 2018
Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune disease, affecting the joints with varying severity among patients. The risk factors include age, gender, genetics, and environmental exposure (cigarette smoking, air pollutants ...
Jacqueline Bullock, Syed A. A. Rizvi, A. Saleh, Sultan S. Ahmed, D. Do, R. Ansari, Jasmin Ahmed   +6 more
semanticscholar   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source