Results 161 to 170 of about 1,101,764 (406)

Cardiovascular Safety During Treatment With Baricitinib in Rheumatoid Arthritis

Arthritis & Rheumatology, 2019
To assess the frequency of cardiovascular and venous thromboembolic events in clinical studies of baricitinib, an oral, selective JAK1 and JAK2 inhibitor approved in more than 50 countries for the treatment of moderately‐to‐severely active rheumatoid ...
P. Taylor, M. Weinblatt, G. Burmester, Terence Rooney, S. Witt, C. Walls, M. Issa, C. A. Salinas, Chadi Saifan, X. Zhang, A. Cardoso, M. González-Gay, T. Takeuchi   +12 more
semanticscholar   +1 more source

Observations on the Treatment of Rheumatoid Arthritis with Butazolidin [PDF]

, 1953
J. P. Currie, Ryanne A. Brown, George F. Will   +2 more
openalex   +1 more source

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source

Dynamic borrowing from historical controls via the synthetic prior with covariates in randomized clinical trials [PDF]

arXiv
Motivated by a rheumatoid arthritis clinical trial, we propose a new Bayesian method called SPx, standing for synthetic prior with covariates, to borrow information from historical trials to reduce the control group size in a new trial. The method involves a novel use of Bayesian model averaging to balance between multiple possible relationships ...
arxiv  

Rheumatoid Arthritis Disease Activity Predicting Incident Clinically Apparent Rheumatoid Arthritis–Associated Interstitial Lung Disease: A Prospective Cohort Study

Arthritis & Rheumatology, 2019
To evaluate rheumatoid arthritis (RA) disease activity and risk of RA‐associated interstitial lung disease (RA‐ILD).
J. Sparks, Xintong He, Jie Huang, Elaine A. Fletcher, A. Zaccardelli, H. M. Friedlander, R. Gill, H. Hatabu, M. Nishino, D. Murphy, C. Iannaccone, Taysir G. Mahmoud, M. Frits, B. Lu, I. Rosas, P. Dellaripa, M. Weinblatt, E. Karlson, N. Shadick, T. Doyle   +19 more
semanticscholar   +1 more source

Spontaneous Rupture of the Tendon of Extensor Pollicis Longus as a Complication of Rheumatoid Arthritis [PDF]

, 1951
Roger C. Harris
openalex   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Associations between exposure to OPEs and rheumatoid arthritis risk among adults in NHANES, 2011-2018 [PDF]

arXiv
Rheumatoid arthritis (RA) has an intricate etiology that includes environmental factors as well as genetics. Organophosphate esters (OPEs) are frequently used as chemical additives in many personal care products and household items. However, there has been limited research on their potential effects on rheumatoid arthritis (RA).
arxiv  

Supervariate Gel Transforms into Various Biominerals in Salt Solutions

Advanced Functional Materials, EarlyView.
It is revealed that common calcium‐based biominerals can form from a stable, non‐toxic ‘supervariate’ gel. This tunable gel selectively yields calcite or hydroxyapatite in carbonate/phosphate solutions, while CaCl₂ facilitates the formation of dihydrate calcium pyrophosphate, which converts to hydroxyapatite upon drying. These findings provide insights
Xinxue Tang, Chong Wang, Yuk‐Tong Cheng, Junda Shen, Yunchen Long, Hongkun Li, Jie Yan, Yang Ren, Xiao Ma, Yufeng Huang, Zhengtao Xu, Jian Lu, Yang Yang Li   +12 more
wiley   +1 more source

Effect of Isolated Soy Protein on Prevention of Rheumatoid Arthritis in Collagen- Induced Rats [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009
Background and ObjectivesThe aim of this study was to investigate the effect of isolated soy protein on prevention of rheumatoid arthritis in collagen-induced rats.
M.R. Rashidi, B. Rashidi, F. Haidari, M. M. Shahi, S.A. Mahboob   +4 more
doaj   +2 more sources