Results 131 to 140 of about 315,994 (289)
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Treating Rheumatoid Arthritis yesterday and today [PDF]
Rheumatoid arthritis is a chronic, systemic inflammatory disorder that mainly affects joints. It is the most common form of inflammatory joint disease, and the second commonest joint disease, osteoarthritis being the commonest.
Mallia, Carmel
core
Association of circulating levels of MMP-8 with mortality from respiratory disease in patients with rheumatoid arthritis. [PDF]
Matrix metalloproteinases (MMPs) are implicated in the destruction of the joint and have been shown to be strongly associated with inflammation in rheumatoid arthritis (RA).
Dawes, PT, Mattey, DL, Nixon, NB
core +1 more source
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai+9 more
wiley +1 more source
Rheumatoid arthritis classification criteria: debatable problems
The paper discusses the issues of imperfect 1987 American College of Rheumatology (ACR) and the 2010 ACR/European League Against Rheumatology (EULAR) rheumatoid arthritis classification criteria and justifies the need for their correction.
Yu. V. Muravyev, A. S. Misiyuk
doaj +1 more source
Associations between exposure to OPEs and rheumatoid arthritis risk among adults in NHANES, 2011-2018 [PDF]
Rheumatoid arthritis (RA) has an intricate etiology that includes environmental factors as well as genetics. Organophosphate esters (OPEs) are frequently used as chemical additives in many personal care products and household items. However, there has been limited research on their potential effects on rheumatoid arthritis (RA).
arxiv
Effect of a small molecule inhibitor of nuclear factor-κB nuclear translocation in a murine model of arthritis and cultured human synovial cells [PDF]
A small cell-permeable compound, dehydroxymethylepoxyquinomicin (DHMEQ), does not inhibit phosphorylation and degradation of IκB (inhibitor of nuclear factor-κB [NF-κB]) but selectively inhibits nuclear translocation of activated NF-κB.
Kubota, Tetsuo+4 more
core +2 more sources
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song+8 more
wiley +1 more source
Effect of a new type of healthy and live food supplement on osteoporosis blood parameters and induced rheumatoid arthritis in Wistar rats [PDF]
Summary Osteoporosis is a skeletal disorder, characterized by a decrease in bone strength and puts the individual at risk for fracture. On the other hand, rheumatoid arthritis is a systemic disease of unknown etiology that causes inflammation of the joints of the organs.
arxiv