Results 151 to 160 of about 213,613 (314)

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Different rheumatoid factor binding patterns distinguish between Sjögren's disease with or without associated RA. [PDF]

RMD Open
Oskam N, Verstappen G, Derksen NIL, Ooijevaar-de Heer P, Bootsma H, Wolbink G, Kroese F, Rispens T.   +7 more
europepmc   +1 more source

Detection of immune complexes. The use of radioimmunoassays with Clq and monoclonal rheumatoid factor. [PDF]

, 1977
Alexandre Gabriel, Vincent Agnello
openalex   +1 more source

On the Nature of the Rheumatoid Factor [PDF]

Annals of the Rheumatic Diseases, 1960
A. Hofmann, W. Müller, F. Wöhler
openaire   +3 more sources

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

Advanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Han   +7 more
wiley   +1 more source

What is rheumatoid factor? From screening to personalized management. [PDF]

Rheumatology (Oxford)
Tanaka Y.
europepmc   +1 more source

Rheumatoid factor IgM autoantibodies control IgG homeostasis. [PDF]

Front Immunol, 2022
Nicolò A, Amendt T, El Ayoubi O, Young M, Finzel S, Senel M, Voll RE, Jumaa H.   +7 more
europepmc   +1 more source

Radioimmunoassay of IgG and IgM Rheumatoid Factors Reacting with Human IgG [PDF]

, 1977
Dennis A. Carson, Simon K. Lawrance, Michael A. Catalano, John H. Vaughan, G N Abraham   +4 more
openalex   +1 more source

Significance of the rheumatoid factor [PDF]

Arthritis & Rheumatism, 1958
openaire   +3 more sources

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

Advanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li, Lei Zhu, Zhaohuai Li, Yihan Zhang, Genxian Zhang, Xuening Peng, Dongting Wu, Qi Jiang, Rong Wang, Renbing Jia, Song Guo Zheng, Wenru Su   +11 more
wiley   +1 more source