Results 261 to 270 of about 213,613 (314)

New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond

Annals of Neurology, EarlyView.
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr., Bruce A. C. Cree, Stephen L. Hauser   +2 more
wiley   +1 more source

Potential Application of a Water‐Soluble Fullerene C60 Decorated with Diethylene Glycol in Treatment of Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
A new ethoxyethanol derivative of iminofullerene, F2, is synthesized and labeled with 99mTc to produce 99mTc‐F2. In vitro, compound F2 inhibits the activation of primary mouse bone marrow‐derived macrophages stimulated with lipopolysaccharide. Moreover, 99mTc‐F2 is selectively enriched in the injured joints of mice. Inflammatory macrophages play a role
Rui He, Alyssa Costello, Yanjie Liu, Weicheng Wang, Zhichang Zhang, Quanjun Cui, Xinlin Yang   +6 more
wiley   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +15 more
wiley   +1 more source

Rheumatoid factor in schizophrenia.

Indian journal of psychiatry, 2011
openaire   +2 more sources

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Rheumatoid Factors and Rheumatoid Arthritis

Scandinavian Journal of Rheumatology, 1988
Rheumatoid factors (RFs) are autoantibodies which bind the Fc region of IgG (1, 2). They can be induced in experimental animals by B cell mitogens and by immunization with a variety of different an...
Timo Palosuo, Markku Heliövaara, K. Aho, Tiinamaija Tuomi   +3 more
openaire   +3 more sources

Rheumatoid Factor

Rheumatic Disease Clinics of North America, 1987
Many human RF-associated crossreactive idiotypes (CRIs) have been defined. Since these CRIs probably are the phenotypic markers of Ig variable region genes, the data suggest that human RFs employ several Ig variable region genes which are common among outbred human populations.
P P, Chen, S, Fong, D A, Carson
openaire   +2 more sources

Rheumatoid factors

Clinical Biochemistry, 1993
Rheumatoid factors (RFs) have been studied for over 50 years and are probably the most written about of any antibody. Nevertheless, the etiology of these RFs and the precise role they play in the pathogenesis of rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) remain a major interest.
T L, Moore, R W, Dorner
openaire   +2 more sources

Imipramine, rheumatoid arthritis and rheumatoid factor

Current Medical Research and Opinion, 1977
SummaryA double-blind placebo-controlled trial was carried out in 20 patients with classical rheumatoid arthritis to study the effect of imipramine on rheumatoid factor titres. Patients were allocated at random to receive 6-weeks treatment with imipramine, in low dosage, or placebo in addition to their antirheumatic medication.
W. C. Dick, D. Spencer, E. T. Robinson, A. Macneill, P. D. Fowler   +4 more
openaire   +3 more sources