Results 81 to 90 of about 315,994 (289)
Objective Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA. Methods We included patients with PsA followed at our prospective observational cohort for the period between 1978 ...
Fadi Kharouf+6 more
wiley +1 more source
Background and Objective: Rheumatoid arthritis is a chronic, inflammatory and systemic disease with peripheral, symmetric polyarthritis symptoms. Several genetic, environmental, and immunological factors contribute greatly to the disease pathogenesis ...
Jafarzadeh L+4 more
doaj
Prediction of drug effectiveness in rheumatoid arthritis patients based on machine learning algorithms [PDF]
Rheumatoid arthritis (RA) is an autoimmune condition caused when patients' immune system mistakenly targets their own tissue. Machine learning (ML) has the potential to identify patterns in patient electronic health records (EHR) to forecast the best clinical treatment to improve patient outcomes.
arxiv
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis [PDF]
Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-adducts are part of the natural antibody pool, while elevated levels of IgG anti-MDA are associated with inflammatory conditions.
arxiv +1 more source
Purification of a Rheumatoid Factor.
SummaryA macroglobulin was purified from sera of individuals with rheumatoid arthritis which agglutinated sensitized sheep erythrocytes and fixed gamma globulin-latex particle suspensions. Tentative evidence for the homogeneity of a preparation was furnished. The isolated macroglobulin is a component of the rheumatoid factor. The latter is a mixture of
Richard H. Freyberg+2 more
openaire +3 more sources
Biomarkers of inflammatory arthritis and proteomics [PDF]
N/
FitzGerald, Oliver+3 more
core +3 more sources
Objective The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients’ self‐reported outcomes after consultation.
Smitha Mathew+6 more
wiley +1 more source
Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. [PDF]
OBJECTIVE:Epigenetic modifications have previously been associated with rheumatoid arthritis (RA). In this study, we aimed to determine whether differential DNA methylation in peripheral blood cell subpopulations is associated with any of 4 clinical ...
Barcellos, Lisa F+13 more
core +1 more source
Objective Walk With Ease (WWE) is a six‐week arthritis‐appropriate evidence‐based physical activity program traditionally offered in a face‐to‐face format. Because many populations encounter participation barriers to in‐person programs, WWE was modified for telephone delivery (WWE‐T).
Christine A. Pellegrini+5 more
wiley +1 more source
Autoantibodies in the Pathogenesis, Diagnosis, and Prognosis of Juvenile Idiopathic Arthritis
Autoantibody production occurs in juvenile idiopathic arthritis (JIA) and numerous other autoimmune diseases. In some conditions, the autoantibodies are clearly pathogenic, whereas in others the roles are less defined.
Shawn A. Mahmud, Bryce A. Binstadt
doaj +1 more source