Results 101 to 110 of about 202,977 (306)

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

open access: yesAdvanced Science, EarlyView.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao   +16 more
wiley   +1 more source

The IBEX Imaging Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluoresence Imaging Methods [PDF]

open access: yesarXiv
The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D and 3D immunofluorescence imaging methods. The design of the Knowledge-Base is modeled after efforts in the open-source software community and includes three facets: a development platform (GitHub), static website, and ...
arxiv  

Refining the adriamycin‐induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study suggested the instability of Adriamycin (ADR) in aqueous solution as the main contributor to large ADR dose variations in literature of the ADR‐induced mouse model of focal segmental glomerulosclerosis (FSGS). We confirmed that freshly prepared ADR solution dosed at 10.5 mg/kg to be optimal in reliably producing FSGS pathology in BALB/c mice
Haochen Jiang   +8 more
wiley   +1 more source

The IBEX Knowledge-Base: Achieving more together with open science [PDF]

open access: yesarXiv
Iterative Bleaching Extends multipleXity (IBEX) is a versatile method for highly multiplexed imaging of diverse tissues. Based on open science principles, we created the IBEX Knowledge-Base, a resource for reagents, protocols and more, to empower innovation.
arxiv  

Monolagen‐Spezifische Struktur und Dynamik von Oberflächen‐ und Polymer‐Gestützten Lipiddoppelschichten

open access: yesAngewandte Chemie, EarlyView.
Das Manuskript untersucht die strukturellen und dynamischen Eigenschaften von Polyethylenglykol‐gestützten Lipiddoppelschichten unter Verwendung einer Methode, die auf Graphen‐induziertem Energietransfer und Line‐Scan‐Fluoreszenz‐Lebenszeit‐Korrelationsspektroskopie basiert. Diese Technik ermöglicht eine subnanometer‐genaue räumliche Auflösung und eine
Narain Karedla   +3 more
wiley   +1 more source

Editorial: Hereditary Periodic Fevers and Autoinflammatory Diseases

open access: yesFrontiers in Pediatrics, 2022
Hafize Emine Sönmez   +2 more
doaj   +1 more source

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