Results 111 to 120 of about 320,397 (244)
Associations of Fire Smoke and Other Pollutants With Incident Rheumatoid Arthritis and Rheumatoid Arthritis–Associated Interstitial Lung Disease
Arthritis &Rheumatology, EarlyView.Objective
The aim of this study was to determine whether pollutants such as fire smoke–related particulate matter <2.5 μm (PM2.5) are associated with incident rheumatoid arthritis (RA) and RA‐associated interstitial lung disease (RA‐ILD). Methods
This patient–control study used Veterans Affairs (VA) data from October 1, 2009, to December 31, 2018.Vanessa L. Kronzer, Yangyuna Yang, Punyasha Roul, James L. Crooks, Cynthia S. Crowson, John M. Davis III, Jeffrey A. Sparks, Jeffrey R. Pierce, Katelyn O'Dell, Brian C. Sauer, Grant W. Cannon, Joshua F. Baker, Ted R. Mikuls, Bryant R. England +13 morewiley +1 more sourceThe use of combination advanced therapies in psoriatic arthritis: results from a UK multi-centre audit. [PDF]
Rheumatology (Oxford)Jethwa H, Gudu T, Coates LC, Helliwell PS, Tillett W, Abuelmagd A, Andev RS, Ashraf M, Baqai T, Choy E, Das D, Gullick N, Heighton C, Kinder A, Laxminarayan R, Mittal G, Morris P, Mukherjee S, Nandagudi A, Rangaraj S, Sharma P, Temple H, Traub B, Paisal V, Hum R, Vivekanantham A, Wilson R, Jadon D. +27 moreeuropepmc +1 more sourceSerum Type I Interferon Score for Prediction of Clinically Meaningful Disease Progression in Limited Cutaneous Systemic Sclerosis
Arthritis &Rheumatology, EarlyView.Objective
To assess the value of serum type I interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial. Methods
A retrospective, longitudinal lcSSc cohort was identified within a national, multicenter observational ...Stefano Di Donato, Rebecca Ross, Ranjitha Karanth, Vishal Kakkar, Enrico De Lorenzis, Lesley‐Anne Bissell, Kristina Clark, Philip Yee, Christopher P. Denton, Francesco Del Galdo +9 morewiley +1 more sourceCorrection: Safety and Efficacy of Bimekizumab in Patients with Psoriatic Arthritis: 2-Year Results from Two Phase 3 Studies. [PDF]
Rheumatol TherMease PJ, Merola JF, Tanaka Y, Gossec L, McInnes IB, Ritchlin CT, Landewé RBM, Asahina A, Ink B, Heinrichs A, Bajracharya R, Shende V, Coarse J, Coates LC. +13 moreeuropepmc +1 more sourceGenome‐Wide Aggregated Trans Effects Analysis Identifies Genes Encoding Immune Checkpoints as Core Genes for Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Objective
The sparse effector “omnigenic” hypothesis postulates that the polygenic effects of common single nucleotide polymorphisms (SNPs) on a typical complex trait are mediated by trans effects that coalesce on expression of a relatively sparse set of core genes.Athina Spiliopoulou, Andrii Iakovliev, Darren Plant, Megan Sutcliffe, Seema Sharma, Cankut Cubuk, Myles Lewis, Costantino Pitzalis, Anne Barton, Paul M. McKeigue +9 morewiley +1 more sourceEfficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial
Arthritis &Rheumatology, EarlyView.Objective
An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.Robert F. Spiera, Valerie Devauchelle‐Pensec, Claire E. Owen, Federico Díaz‐González, Tsutomu Takeuchi, Edit Drescher, Jaclyn Anderson, Dilek Arikan, Ronilda D'Cunha, Julie Parmentier, Denise T. Kruzikas, Weihan Zhao, Yang Yang, Karen Stellpflug, Frank Buttgereit +14 morewiley +1 more sourceIxekizumab Retention Rate and Predictors of Treatment Persistence in Psoriatic Arthritis: Results of an Italian Multicenter Study. [PDF]
J Psoriasis Psoriatic ArthritisMazzanti C, Paroli M, Santoboni G, Addimanda O, Raffeiner B, Bezzi A, Visalli E, Celletti E, Farina A, Bernardi S, Larosa M, Andracco R, Del Medico P, Colella Molica AB, Giuggioli D, Lumetti F, Sandri G, Priora M, Serale F, Nucera V, Ometto F, Bravi E, Lo Gullo A, Scolieri P, Parisi S, Ravagnani V, Vitetta R, Marchetta A, Becciolini A, Angrisani C, De Simone M, Caccavalle R, Reta M, Magnani M, Mascella F, Foti R, Amato G, De Lucia F, Dal Bosco Y, Foti R, Di Penta M, Sabatini E, Del Biondo P, Girelli F, Camellino D, Bianchi G, Mansueto N, Smerilli G, Franchina V, Salvarani C, Ianniello A, Giampietro C, Di Donato E, Santilli D, Lucchini G, Arrigoni E, Platè I, Bruzzese V, Fusaro E, Ditto MC, Murgia D, Rovera G, Volpe A, Ferrero G, Adorni G, Molica FC, Ariani A. +66 moreeuropepmc +1 more source