Results 151 to 160 of about 202,977 (306)

Rheumatology in Singapore [PDF]

open access: yesRheumatology, 1997
P H Feng, Kok-Yong Fong, M L Boey
openaire   +2 more sources

Association of Synovial Innate Immune Exhaustion With Worse Pain in Knee Osteoarthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Uncontrolled pain remains a major clinical challenge in the management of knee osteoarthritis (OA), the most common disabling joint disease. Worse pain is associated with synovial innate immune cell infiltration (synovitis), but the role of innate immune‐regulatory cells in pain is unknown. Our objective was to identify synovial innate immune
Holly T. Philpott   +14 more
wiley   +1 more source

Disturbed Spatial WNT Activation—A Potential Driver of the Reticularized Skin Phenotype in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Little is known on the mechanisms necessary to maintain the physiologic adult human skin integrity. This study aims to quantitatively describe anatomic changes in systemic sclerosis (SSc)–skin compared with controls and investigate the underlying mechanisms.
Sara Chenguiti Fakhouri   +18 more
wiley   +1 more source

Metabolic Stress Expands Polyfunctional, Proinflammatory Th17 Cells in Patients With Psoriatic Arthritis for Whom There is Interleukin‐23–Independent Interleukin‐17 Production

open access: yesArthritis &Rheumatology, EarlyView.
Objective Genetic associations and blockade of the interleukin (IL)‐23/IL‐17 axis with monoclonal antibodies support a role for this pathway in patients with psoriatic arthritis (PsA). This study examines the requirement of IL‐23 for IL‐17 production and the role of the metabolic microenvironment in the expansion of Th17‐derived cells in patients with ...
Carmel B. Stober   +4 more
wiley   +1 more source

Regulatory T cell‐derived interleukin‐15 promotes the diversity of immunological memory

open access: yesEuropean Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
We investigated the identity of IL‐15 producing cells using several mouse strains with cell type‐specific loss of IL‐15 expression. After the resolution of acute infection, IL‐15 secreted by regulatory cells, but not skeletal muscles or myeloid cells, was required for the maintenance of a subset of memory cells referred to as terminal effector memory T
Alaa Madi   +12 more
wiley   +1 more source

Social media in advancing equity and collaboration in rheumatology: the CORDIALITY review. [PDF]

open access: yesRMD Open
Hmamouchi I   +12 more
europepmc   +1 more source

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