Results 201 to 210 of about 310,012 (268)

Cardio‐Rheumatology: At the Intersection of Inflammation, Immunity, and Cardiovascular Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Brittany N. Weber, Monica Mukherjee
doaj   +1 more source

Patient Profile and Diagnostic Distribution in a Turkish Rheumatology Outpatient Clinic: A Prospective 2-Month Analysis. [PDF]

Eurasian J Med
Cilli Hayıroğlu S, İğneci E.
europepmc   +1 more source

Exome Sequencing Uncovers Phenotypic and Genotypic Heterogeneity in 196 Indian Families Evaluated for Autoinflammatory Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autoinflammatory disorders (AIDs) are a clinically heterogeneous group of inborn errors of immunity primarily caused by dysregulation in the innate immune system. Clinical diagnosis is often challenging due to clinical heterogeneity and the overlapping phenotypes with other inborn errors of immunity and monogenic conditions that mimic AIDs ...
Vaishnavi Ashok Badiger, Periyasamy Radhakrishnan, Suma Balan, Anand P. Rao, Prajna Udupa, Karthik Vijay Nair, Bhagesh Hunakunti, Adarsh Pooradan Prasannakumar, Sanket Limaye, Huzail Gani Shaikh, Rohit Naik, Mahesh Janarthanan, Sudharshan Sridharan, Vishal Sondhi, Sheela Nampoothiri, Hitesh Shah, Sabrinath Mahadevan, Mahabaleshwar Mamadapur, Devang Pandya, Katta Mohan Girisha, Abhay Shivpuri, Amita Moirangthem, Jyothi Raghuram, Gandham Sri Lakshmi Bhavani, Sachin Jeevanagi, Girish Subramaniam, Amita Aggarwal, Anju Shukla, Dhanya Lakshmi Narayanan   +28 more
wiley   +1 more source

Building the future of patient-centred research: an EULAR PARE community of practice advancing patient research partner involvement in rheumatology. [PDF]

EULAR Rheumatol Open
de Wit M, Stevens M, Aouad K, Boyd P, Caeyers N, Carmona L, Chingov K, De Cock D, Dey M, Edwards CJ, Elhai M, Gossec L, de Groot I, Makri S, Pennings P, Primdahl J, Rodrigues D, Stones SR, Studenic P, Esbensen BA.   +19 more
europepmc   +1 more source

Adipose‐derived mesenchymal stem cell injection into the KI10 acupoint mitigates cartilage damage in KOA rats through PGE2‐mediated α7nAChR/NF‐κB pathway

Animal Models and Experimental Medicine, EarlyView.
In our research, KOA rat models were established and treated with ADSC injection into the KI10 acupoint. Pain relief, behavioral function, and joint structural improvements were systematically assessed using ethological tests, imaging, histopathological staining, transmission electron microscopy, and molecular analyses.
Mengwei Dong, Wenfang Li, Wanpeng Yang, Te Ba, Nan Nan, Yang Liu, Jing Han, Huiqin Hao   +7 more
wiley   +1 more source

Evaluating a guideline-aligned prednisone threshold within the Lupus Low Disease Activity State (LLDAS): associations with damage accrual. [PDF]

RMD Open
Parodis I, Andraos R, Bottai M, Sjöwall C.   +3 more
europepmc   +1 more source

Construction and evaluation of a chronic arthritis animal model induced by persistent activation of toll‐like receptors via lipopolysaccharide stimulation

Animal Models and Experimental Medicine, EarlyView.
We constructed a novel systemic juvenile idiopathic arthritis mouse model (LC) by introducing sustained TLR4 activation into the collagen‐induced arthritis model. The LC model effectively recapitulates human sJIA‐like systemic inflammation while revealing a critical dissociation between systemic immune activation and joint damage.
Fengming Li, Qiang Luo, Xinglin Wu, Yuxiao Chen, Xuemei Tang   +4 more
wiley   +1 more source

Comparative evaluation of disease activity measures for adult-onset Still's disease: a multicentre, retrospective, cohort study. [PDF]

RMD Open
Vordenbäumen S, Filla T, Friedrich R, Blank N, Ernst D, Henes J, Keyßer G, Klemm P, Krusche M, Meinecke A, Rech J, Schulz N, Petzinna SM, Pankow A, Schäfer VS, Pfeil A, Klapa S, Pongratz G, Feist E, Kernder A.   +19 more
europepmc   +1 more source

Engineered 3D Fibronectin‐Based Environments Modulate the Pathogenic Profile of Arthritic Synovial Fibroblasts

Advanced NanoBiomed Research, EarlyView.
Fibroblast behavior is shaped by the surrounding microenvironment, yet conventional culture systems often fail to capture disease‐relevant phenotypes. Here, platform‐dependent responses of healthy and arthritic synovial fibroblasts are examined across 2D and 3D culture systems. Distinct inflammatory and proliferative signatures emerge, highlighting how
Aneesah Khan, Piaopiao Pan, Yanling Lan, Çağlar Çi̇l, Julia Isakova, Yilin Wang, Theodora Rogkoti, Thanutchaporn Sartyoungkul, James F. C. Windmill, Jonathan William, Manuel Salmeron‐Sanchez, Margaret H. Harnett, Oana Dobre, Miguel A. Pineda   +13 more
wiley   +1 more source

Association between canakinumab dose and long-term remission in Still's disease: insights from the AIDA network registry. [PDF]

Front Pharmacol
Vitale A, Caggiano V, Sbalchiero J, Lopalco G, Tufan A, Ragab G, Sfikakis PP, Dagna L, Batu ED, Ozen S, Conti F, Maiolini F, Bugatti S, Frassi M, Ruscitti P, Morrone M, La Torre F, Cakir IY, Akay N, Kilic Konte E, Laskari K, Bilginer Y, Gattamelata A, Croce J, De Stefano L, Voltarel G, Cipriani P, Maggio MC, Al-Mayouf SM, Fotis L, Rigante D, Sota J, Verrecchia E, Guggino G, La Barbera L, Piga M, Emmi G, Gallizzi R, Conti G, Sfriso P, Bartoloni E, Giacomelli R, Barone P, Olivieri AN, Alemanno A, Lo Gullo A, Direskeneli H, Alibaz-Oner F, Karamanakos A, Prete M, Edrees A, Gavioli F, Parronchi P, Ciccia F, Cardamone C, Hernández-Rodríguez J, Hatemi G, Bes C, Almaghlouth IA, Marhuenda ÁR, Gonzáles-García A, Gaggiano C, De Paulis A, Tezcan ME, Brucato AL, Feist E, Tornero-Romero F, Suzon B, Ogunjimi B, Thabet M, Conforti A, Pucino V, Boyarchuk O, Kovalchuk T, Govoni M, Iagnocco A, Chimenti MS, Moshrif A, Del Giudice E, Carubbi F, Erten Ş, Tharwat S, Hegazy MT, Więsik-Szewczyk E, Torres-Ruiz J, Martín-Nares E, Balistreri A, Fabiani C, Frediani B, Hinojosa-Azaola A, Kasapçopur Ö, Cantarini L.   +91 more
europepmc   +1 more source