Results 41 to 50 of about 202,977 (306)
Abstract Rheumatological diseases include conditions which affect limited regions of the locomotor system only and also conditions which can have widespread systemic affects. The rheumatological history must reflect both of these aspects. The main symptoms of joint disease are pain, stiffness, swelling and deformity.
Jennifer G Worrall, Jane Dacre
openaire +2 more sources
ABSTRACT Febrile infection related epilepsy syndrome (FIRES) is a rare presentation of refractory status epilepticus with immune dysregulation as a potential pathologic mechanism. Despite promising results from second‐line immunomodulators, approximately 30% remain refractory to treatment.
Kristen S. Fisher+5 more
wiley +1 more source
Objective A simple, scalable tool that identifies psoriasis patients at high risk for developing psoriatic arthritis (PsA) could improve early diagnosis. We aimed to develop a risk prediction model for the development of PsA and to assess its performance among patients with psoriasis.
Lihi Eder+8 more
wiley +1 more source
Objetivo: describir los diferentes perfiles, en términos de calidad de vida relacionada con la salud, en pacientes con enfermedades crónicas en una institución de salud de alta complejidad. Metodología: estudio transversal descriptivo.
Juan Guillermo Barrientos Gómez+5 more
doaj +1 more source
Objective The National Institute of Health and Care Excellence (NICE) criteria for osteoarthritis (OA) obviate the need for physical examination or imaging, and their use may improve timely diagnosis of OA. However, they have not been validated. Methods Within a larger study of individuals with type 2 diabetes, participants with and without self ...
Lauren K. King+6 more
wiley +1 more source
Global Rheumatology launches its Portuguese version
The articles in the journal will be available in Spanish, English, and Portuguese, aiming to reach all audiences and acknowledge the importance of research and science being produced in our region.
Fernando Neubarth , Estefania Fajardo
doaj +1 more source
Foundations of a Knee Joint Digital Twin from qMRI Biomarkers for Osteoarthritis and Knee Replacement [PDF]
This study forms the basis of a digital twin system of the knee joint, using advanced quantitative MRI (qMRI) and machine learning to advance precision health in osteoarthritis (OA) management and knee replacement (KR) prediction. We combined deep learning-based segmentation of knee joint structures with dimensionality reduction to create an embedded ...
arxiv +1 more source
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner+12 more
wiley +1 more source
Immunomics in Pediatric Rheumatic Diseases
The inherent complexity in the immune landscape of pediatric rheumatic disease necessitates a holistic system approach. Uncertainty in the mechanistic workings and etiological driving forces presents difficulty in personalized treatments. The development
Shi Huan Tay+10 more
doaj +1 more source
Objective Osteoporosis, a known complication of rheumatoid arthritis (RA), increases the risk of hip fracture, which is associated with high morbidity and mortality. Fracture risk estimates in patients with RA treated with contemporary treatment strategies are lacking.
C. Allyson Jones+5 more
wiley +1 more source