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Emerging drugs for perennial allergic rhinitis
Expert Opinion on Emerging Drugs, 2012Allergic rhinitis (AR) is a high-prevalence disease, sustained by an IgE-triggered reaction with histamine release, followed by an inflammatory response which involves cells, mediators, cytokines and adhesion molecules. According to its duration, AR can be either intermittent or persistent.
Passalacqua,G, Ciprandi,G
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2018
Compared with seasonal allergic rhinitis (SAR), exposure to allergens on a year-around basis leads to persistent symptoms that can be associated with significant impairment of quality of life. As is the case with SAR, management of perennial allergic rhinitis (PAR) entails aeroallergen avoidance, pharmacotherapy, and in properly select cases allergen ...
Martin A. Smith, David M. Lang
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Compared with seasonal allergic rhinitis (SAR), exposure to allergens on a year-around basis leads to persistent symptoms that can be associated with significant impairment of quality of life. As is the case with SAR, management of perennial allergic rhinitis (PAR) entails aeroallergen avoidance, pharmacotherapy, and in properly select cases allergen ...
Martin A. Smith, David M. Lang
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Oral Vasoconstrictors in Perennial Non‐Allergic Rhinitis
Allergy, 1982Nasal airway resistance and nasal symptoms were evaluated in patients with perennial non‐allergic rhinitis before and after vasoconstrictory drugs and placebo taken orally. The patients were partly selected; these suffering mainly from nasal obstruction being tested.
P, Broms, L, Malm
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Practice Nursing, 1998
The nose is the first part of the natural airway, a fact often forgotten by doctors and nurses alike. Airflow in the nose is rapid, and during a sniff it ean easily reach the speed of a hurricane! It draws in all the airborne pollutants and particles and filters most of them out of the inhaled air before they reach the sensitive lining of the lungs ...
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The nose is the first part of the natural airway, a fact often forgotten by doctors and nurses alike. Airflow in the nose is rapid, and during a sniff it ean easily reach the speed of a hurricane! It draws in all the airborne pollutants and particles and filters most of them out of the inhaled air before they reach the sensitive lining of the lungs ...
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Neuronal Plasticity in Persistent Perennial Allergic Rhinitis
Journal of Occupational and Environmental Medicine, 2005Persistent perennial allergic rhinitis belongs to the most frequent diseases in occupational and environmental medicine. Because the innervation may play a role in the pathogenesis of the disease, the present study analyzed nasal mucosal nerve profiles.Neuropeptide-containing nerve fibers were examined using immunohistochemistry and related to ...
Axel, Fischer +9 more
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Eosinophil Cationic Protein in Perennial Allergic Rhinitis
Auris Nasus Larynx, 1995For a quantitative investigation of eosinophil activation in perennial allergic rhinitis, eosinophil cationic protein (ECP) concentrations were measured by a radioimmunoassay in serum, nasal secretions (ECPWN) and in the supernatant of these nasal secretions (ECPsup) obtained from normal subjects and allergic patients.
K, Hisamatsu +4 more
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Pathophysiology of perennial allergic rhinitis
Allergy, 1997Allergic rhinitis involves an early phase, largely mediated through mast cells, and a late phase which involves cellular infiltration and mediator release. In the early phase, mast cells release mediators as a result of antigen cross‐linking adjacent immunoglobulin E molecules bound to mast cell surfaces.
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