Results 181 to 190 of about 161,428 (309)

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Patients With Isolated Nail Psoriasis Are at Increased Risk for Asthma Compared to Controls in a Retrospective Cohort Study at a Single Academic Institution

Dermatology Practical & Conceptual
Rachel C Hill, Rhiannon C Miller, Shari R Lipner   +2 more
doaj   +1 more source

Self-reported respiratory allergic symptoms and eczema in schoolchildren in Peja region-west Kosovo. [PDF]

Sci Rep
Lumezi BG, Lokaj-Berisha V, Zhjeqi V, Tahirbegolli B, Hajrushi AB, Ahmetaj L.   +5 more
europepmc   +1 more source

Emerging Risk: Intranasal Tin Exacerbates Allergic Rhinitis in Humans and Mice

Allergy, EarlyView.
Delgama A. S. M. Nishadhi, Shogo Sumiya, Akira Tazaki, Takumi Kagawa, Mohamed Abdelmoneim, Masafumi Sakashita, Kazuhiro Ogi, Shigeharu Fujieda, Shinichi Iwasaki, Masashi Kato   +9 more
wiley   +1 more source

Microarrayed Allergen Molecules Distinguish IgE Sensitisation to Blomia tropicalis and Dermatophagoides pteronyssinus

Allergy, EarlyView.
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza, Siratcha Phanthong, Huey‐Jy Huang, Milena Weber, Eszter Sarzsinszky, Petra Zieglmayer, Gabrielle Pauli, Margarete Focke‐Tejkl, Mikhail Tulaev, Nikolina Todorovic, Walter Keller, Thomas Schlederer, Luis Caraballo, Anchalee Tungtrongchitr, Rudolf Valenta, Pongsakorn Tantilipikorn, Susanne Vrtala   +16 more
wiley   +1 more source

Standardization of Nasal Cytology: An Expert-based Delphi Consensus. [PDF]

Curr Allergy Asthma Rep
Macchi A, Gelardi M, Landi M, Gramellini G, Giancaspro R, Nappi L, Imperatore C, Bocciolini C, Seccia V, Pecoraro P, Arnone F, Rossi V, Heffler E, all AICNA members.   +13 more
europepmc   +1 more source

Prediction of allergic disease trajectories from birth up to adolescence. [PDF]

Pediatr Allergy Immunol
Leskien M, Scheerer M, Thiering E, Kress S, Coffey C, Berdel D, von Berg A, Bauer CP, Gappa M, Heinrich J, Koletzko S, Schikowski T, Koletzko B, Peters A, Standl M.   +14 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Identification of allergic rhinitis-related genes and mediating immune cells based on cis-eQTL: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Peng J, Yan X, Shen M, Xuan J, Chen S.
europepmc   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source