Results 191 to 200 of about 161,428 (309)

Elevated CO2 and Temperature Alter Grass Pollen's Ability to Modify Transcriptome and Function of the Nasal Epithelium

open access: yesAllergy, EarlyView.
We exposed human nasal epithelial tissues to pollen from grasses grown under different climate treatments (temperature and CO2). Pollen weakened epithelial tight junctions and altered cytokine‐related gene expression, with similar protein‐level effects.
Tarleena Tossavainen   +5 more
wiley   +1 more source

Safety and Effectiveness of Subcutaneous Immunotherapy with a Glutaraldehyde-Polymerized Mite Allergen Extract in Adults and Children with Allergic Rhinitis with or Without Asthma Due to <i>Dermatophagoides</i>. [PDF]

open access: yesDiseases
Verdeguer Segarra O   +10 more
europepmc   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

open access: yesAllergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery   +25 more
wiley   +1 more source

Circulating Type 2 Memory B Cell Frequency Is a Biomarker for Allergen Immunotherapy Efficacy in Patients With Allergic Rhinitis

open access: yes
Allergy, EarlyView.
Yue Ma   +10 more
wiley   +1 more source

A One‐Strength Dose Escalation Regimen for Birch Pollen SCIT Is Safe and Tolerable in Children, Adolescents, and Adults

open access: yesAllergy, EarlyView.
This study evaluated safety and tolerability of birch pollen SCIT during dose escalation with a new One‐Strength regimen (3 injections, Strength B) compared to the Standard regimen (7 injections, Strengths A and B) in patients aged 5–65 years. Safety and tolerability were comparable between the two regimens in adults, adolescents, and adolescents, as ...
Marek Jutel   +5 more
wiley   +1 more source

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