Results 61 to 70 of about 156,275 (343)

Exploring the role of indoor microbiome and environmental characteristics in rhinitis symptoms among university students

open access: yesFrontiers in Microbiomes
IntroductionRhinitis is one of the most prevalent chronic respiratory diseases worldwide. There is emerging evidence suggesting that the indoor microbiome may contribute the onset and exacerbation of rhinitis symptoms, but comprehensive studies on this ...
Xi Fu   +6 more
doaj   +1 more source

Long-acting topical decongestants

open access: yesМедицинский совет, 2020
Significant role of getting the required amount of air into the human body belongs to the breathing by the nose. The nasal cavity prepares the air for reciprocity with the lower respiratory tract owing to the complex structure of the mucous membrane ...
A. Yu. Ovchinnikov   +3 more
doaj   +1 more source

Efficacy and Safety of ABBV‐154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo‐Controlled Trial

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Despite availability of biologics and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit   +13 more
wiley   +1 more source

Increasing Prevalence of Allergic Rhinitis in China

open access: yesAllergy Asthma and Immunology Research, 2018
Allergic rhinitis (AR) is a critical public health, medical and economic problem in China. AR is also an important risk factor which will cause many diseases or disorders, especially in children.
Yuan Zhang, Luo Zhang
semanticscholar   +1 more source

Mechanisms of Rhinitis

open access: yesAllergy and Asthma Proceedings, 1998
Mast cell degranulation leads to the release of histamine and a host of other mediators. However, histamine remains preeminent in proffering the vexatious symptoms of allergic rhinitis including itching, sneezing, dripping, and congestion. The mechanisms of symptom production in rhinitis will be reviewed with an eye toward effects on mucosal resident ...
openaire   +4 more sources

First‐in‐human safety, tolerability, pharmacokinetics and pilot food‐effect study of the candidate antimalarial compound MMV367

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle   +13 more
wiley   +1 more source

Classification of Nonallergic Rhinitis Syndromes With a Focus on Vasomotor Rhinitis, Proposed to be Known henceforth as Nonallergic Rhinopathy

open access: yesWorld Allergy Organization Journal, 2009
Many patients have nasal syndromes that are nonallergic and noninfectious and not caused by mechanical or anatomic abnormalities. There are at least 8 recognized nonallergic rhinitis syndromes: drug-induced rhinitis including rhinitis medicamentosa ...
Michael A. Kaliner, MD
doaj  

Recent developments and highlights in allergic rhinitis

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2019
Allergic rhinitis (AR) is a disease with high prevalence all over the world and therefore needs to be thoroughly investigated and treated accordingly. The mechanisms underlying the pathology and treatment of AR have been widely studied, but many aspects ...
Y. Meng, Chengshuo Wang, Luo Zhang
semanticscholar   +1 more source

Exposure to pseudoephedrine during pregnancy and major congenital malformations: Findings from a large population‐based cohort of pregnancies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to assess the risk of major congenital malformations following first‐trimester pseudoephedrine (PSE) exposure. Methods A population‐based observational cohort study was conducted on pregnancies of women aged 15–49 years, insured by Clalit Health Services in southern Israel, who gave birth or had elective ...
Saar Dor   +7 more
wiley   +1 more source

Epidemiology of Vasomotor Rhinitis

open access: yesWorld Allergy Organization Journal, 2009
Vasomotor rhinitis is the most common form of nonallergic rhinitis, comprising approximately 71% of all nonallergic rhinitis conditions. Although the epidemiology of this subtype of nonallergic rhinitis has not been definitively studied, it is estimated ...
Russell A. Settipane, MD
doaj  

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