Results 161 to 170 of about 41,193 (285)

Biologics in pediatric chronic rhinosinusitis with nasal polyps: A systematic review of efficacy and safety. [PDF]

Pediatr Allergy Immunol
Loperfido A, Anzivino R, Galletti C, Moffa A, Stivalini D, La Mantia I, De Corso E.   +6 more
europepmc   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Comment on "Early and Sustained Improvements in Sense of Smell With Tezepelumab Treatment in Patients With Chronic Rhinosinusitis With Nasal Polyps (WAYPOINT)". [PDF]

Int Forum Allergy Rhinol
Malik MMUD.
europepmc   +1 more source

Dissociated Biologic Responses Across the United Airway: A Case Report of Severe Asthma With Chronic Rhinosinusitis With Nasal Polyps and Eosinophilic Otitis Media. [PDF]

Respirol Case Rep
Tajiri T, Takemoto N, Minakata T, Suzuki M, Ozawa Y, Ohkubo H.   +5 more
europepmc   +1 more source

Correlation of Local Nasal Biomarkers and Olfactory Dysfunction in Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis. [PDF]

Int Forum Allergy Rhinol
ABSTRACT Background To systematically evaluate the local biomarkers correlated with olfactory dysfunction (OD) in chronic rhinosinusitis (CRS). Methods A systematic review was conducted in CINAHL, Cochrane Library, PubMed, and Scopus from inception to July 2025.
Kayekjian D, Gandra N, Nguyen SA, Twardus SW, Schlosser RJ.   +4 more
europepmc   +2 more sources

Infraorbital Ethmoid Cells (Haller Cells) and Their Role in Chronic Rhinosinusitis: An Evidence-Based Meta-Analysis. [PDF]

Life (Basel)
Nedelcu AH, Anton E, Andrei MB, Frăsinariu OE, Knieling A, Lupu A, Tepordei RT, Partene Vicoleanu SA, Statescu G, Ursaru M, Rusu DC, Anton SC, Morariu ID, Mitrea M, Lupu VV.   +14 more
europepmc   +1 more source

Complement–Eosinophil Crosstalk Links Complement Activation to Fibrin Deposition in Eosinophilic Chronic Rhinosinusitis

Allergy, EarlyView.
Ryo Hasegawa, Shigeharu Ueki, Misaki Arima, Shohei Nishiyama, Keinosuke Hizuka, Kohei Tatsumi, Ayako Sawai, Anna Shimizu, Yuki Sonoda, Eiichi Kato, Masanori Kidoguchi, Masafumi Sakashita, Yohei Sato, Atsushi Kato, Bruce K. Tan, Robert C. Kern, Robert P. Schleimer, Shigeharu Fujieda, Yoshimasa Imoto   +18 more
wiley   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Reply to: Comment on "Female-Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital-Based Cohort Study From the Taiwan Precision Medicine Initiative". [PDF]

Int Forum Allergy Rhinol
Jiang RS, Chen YC.
europepmc   +1 more source

Nasal Obstruction Is Reduced 5–7 Years After Radiofrequency Turbinate Reduction: Results From a Retrospective Observational Cohort Study

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Nasal obstruction, often caused by structural and inflammatory conditions, is prevalent and significantly impacts health‐related quality of life. Radiofrequency Turbinate Reduction (RFTR) is a widely employed treatment for inferior turbinate hypertrophy, yet evidence of its long‐term effectiveness remains limited. This study aimed
Veronica Ahlund, Pål Rosholm Comstedt, Maria Värendh, Pernilla Sahlstrand‐Johnson   +3 more
wiley   +1 more source