Results 211 to 220 of about 37,461 (298)

Impact of Biologics on Oscillometry Defined Small Airway Dysfunction in Uncontrolled Asthma

Clinical &Experimental Allergy, EarlyView.
Forced oscillometry technique defined small airways dysfunction as a treatable trait in asthma. Monoclonal antibodies can improve small airways dysfunction, but their effects vary by mechanism of action. ABSTRACT Small airways dysfunction (SAD) is a recognised treatable trait within severe asthma, associated with worse symptom control and increased ...
Robert Greig, Philipp Suter, Rory Chan, Brian Lipworth   +3 more
wiley   +1 more source

Association of Obstructive Sleep Apnea Risk with Hypoxia-Inducible Factor Expression in Chronic Rhinosinusitis by Inflammatory Endotype. [PDF]

J Clin Med
Min HK, Kim SW, Min JY.
europepmc   +1 more source

RNA binding protein ZFP36L1 promotes ferroptosis in chronic rhinosinusitis by destabilizing CAMK2A mRNA and impairing mitochondrial quality control. [PDF]

Clin Transl Med
Xiong J, Zhang S, Li C, Ai Y, Liu X, Liu Y, Liu H.   +6 more
europepmc   +1 more source

Short-term high-dose budesonide nasal spray for postoperative uncontrolled chronic rhinosinusitis: A randomized controlled trial. [PDF]

World Allergy Organ J
Li Y, Liu Y, Zhao J, Zeng X, Tang Z, Liu Y, Li C, Shi J, Chen F.   +8 more
europepmc   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Preventing sino-nasal polyposis recurrence after functional endoscopic sinus surgery: a multicentric study. [PDF]

Am J Clin Exp Immunol
Omer GL.
europepmc   +1 more source

Are Phenotypic Baseline Characteristics Related to Abolition of AHR After Benralizumab and Dupilumab?

Clinical &Experimental Allergy, EarlyView.
Philipp Suter, Robert Greig, Rory Chan, Brian J. Lipworth   +3 more
wiley   +1 more source

Endoscopic excision of a unilateral sinonasal hamartoma. [PDF]

J Surg Case Rep
Witte C, Dillard DJ, Segal S, Fortson JK.   +3 more
europepmc   +1 more source

Tezepelumab Reduces Alarmin Cytokine Levels in Upper Airway Epithelial Cells in Patients With Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Hazel Marriott, Adil Adatia, Subhabrata Moitra, Paige Lacy   +3 more
wiley   +1 more source

A new era beckons in asthma: enhanced models of care, disease remission, artificial intelligence and consumer participation

Internal Medicine Journal, EarlyView.
Abstract The landscape of asthma management is undergoing significant transformation. This change is driven by several factors: deeper understanding of asthma pathophysiology, appreciation of the long‐term harm of oral corticosteroids, biological treatments that dramatically improve patient outcomes with asthma remission becoming a realistic goal, and ...
John Politis, Kerry Hancock, Jo A Douglass, Paul Leong, Philip Bardin   +4 more
wiley   +1 more source