Results 211 to 220 of about 92,697 (378)

Getting involved in ENT clinical research in the UK; how can the NIHR Clinical Research Network help? [PDF]

, 2014
Bhutta, Mahmood, Blackshaw (UCL), Helen, Philpott, Carl, Schilder, Anne   +3 more
core   +1 more source

A Prospective Study of Anatomical Variations of Osteomeatal Complex in Chronic Rhinosinusitis

BLDE University
openalex   +1 more source

Double-blind placebo-controlled randomized clinical trial of verapamil for chronic rhinosinusitis with nasal polyps [PDF]

, 2017
Marcel M. Miyake, Angela L. Nocera, Patricia A. Levesque, Rong Guo, Christine Finn, Jeremy Goldfarb, Stacey T. Gray, Eric H. Holbrook, Nicolas Y. Busaba, José Eduardo Lutaif Dolci, Benjamin S. Bleier   +10 more
openalex   +1 more source

Determination of the effect of topical application of N-acetylcysteine on the recovery rate of patients with chronic rhinosinusitis after surgical treatment, based on SNOT-22 test scores

, 2023
Anton Falko, Oleksandr Naumenko
openalex   +2 more sources

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Orbital complications in allergic fungal rhinosinusitis: a case series from a tertiary center hospital experience. [PDF]

AME Case Rep
Alabdulaal MR, Aljubran HJ, Alfaleh MA, Eksail SH, Ashoor MM, Alahmari MS, Almomen A.   +6 more
europepmc   +1 more source

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

Allergy, EarlyView.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang, Jing Liu, Jing Ye, Li‐Ying Sun, Hsiao Hui Ong, Yang Peng, Bing‐Qi Lin, Jun‐Hao Tu, Ke‐Shuang Wang, Yi‐Shan Xiong, Qing Luo, Mark Thong, Yu Xu, De‐Yun Wang   +13 more
wiley   +1 more source

Autoallergy in chronic rhinosinusitis and its clinical relevance. [PDF]

World Allergy Organ J
Sánchez J, Sánchez A, Arango J, Martinez D, Puerta L.   +4 more
europepmc   +1 more source

Clinical feature-based diagnosis criteria of eosinophil and non-eosinophil chronic rhinosinusitis in Taiwan

Liang‐Chun Shih
openalex   +2 more sources

“Super‐Responders” to Dupilumab Treatment in Patients With Primary Diffuse Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study aimed to evaluate the feasibility of extending dupilumab dosing intervals in T2‐CRSwNP by assessing how many patients maintain disease control with once‐every‐12‐weeks (Q12W) dosing and comparing clinical characteristics of super‐responders and excellent responders. Tapering of dupilumab to Q12W appears feasible in super‐responding patients.
P. E. Vonk, J. J. Otten, H. B. E. Elzinga, R. J. L. van der Lans, G. F. J. P. Adriaensen, L. B. L. Benoist, D. R. Hoven, W. J. Fokkens, S. Reitsma, PolyREG Consortium, A.B. Rinia, I. Krebbers, I.J. Kleiss, M. E. Cornet   +13 more
wiley   +1 more source