Results 91 to 100 of about 60,470 (243)

IL-17 Modulation of Rhinovirus-Induced Allergic Airways Disease [PDF]

open access: yes, 2014
Asthma is a chronic inflammatory disease of the airways, resulting in significant morbidity and premature deaths. Rhinoviruses, agents of the common cold, have been identified as the most frequent viruses inducing asthma exacerbations.
Peel, Tamlyn Jolyon Robert
core   +1 more source

Pseudomonas aeruginosa rhamnolipids stabilize human rhinovirus 14 virions

open access: yesJournal of Virology
Many mammalian viruses encounter bacteria and bacterial molecules over the course of infection. Previous work has shown that the microbial ecology of the gut plays an integral role in poliovirus and coxsackievirus infection, where bacterial glycans can ...
Joshua J. Baty   +2 more
doaj   +1 more source

Viruses exacerbating chronic pulmonary disease: the role of immune modulation

open access: yesBMC Medicine, 2012
Chronic pulmonary diseases are a major cause of morbidity and mortality and their impact is expected to increase in the future. Respiratory viruses are the most common cause of acute respiratory infections and it is increasingly recognized that ...
Singanayagam Aran   +3 more
doaj   +1 more source

The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley   +1 more source

IgE running interference for rhinovirus?

open access: yes, 2017
Anti-IgE treatment in pediatric allergic asthmatics reduces rates of symptomatic rhinovirus infection.
Sarah E. Henrickson
core   +1 more source

Modeling Asthma in Mice Using Rhinovirus Infection

open access: yes, 2023
Rhinovirus (RV) infection is linked to early life wheezing and exacerbation of adult asthma. RV infection can be modeled in adult and neonatal mice. This chapter outlines methods for the production of standardized human rhinovirus A1B and mouse infection.
Bentley, JK
core   +1 more source

INnovative Steroid Treatment to reduce Asthma development in children after first-time Rhinovirus-induced wheezing (INSTAR): protocol for a randomised placebo-controlled trial

open access: yesBMJ Open
Introduction Asthma is a leading cause of morbidity and healthcare use among children. Risk factors of childhood asthma include atopic predisposition and severe wheezing episodes caused by rhinovirus infection in early life.
Maria Vollsæter   +21 more
doaj   +1 more source

A Cross‐Country Evaluation of Respiratory Syncytial Virus and Human Metapneumovirus Surveillance Systems: Identifying Gaps and Best Practices for Improved Disease Monitoring

open access: yesReviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are seasonal respiratory viruses that can cause severe outcomes, particularly in older adults; however, their burden remains under‐captured. The World Health Organisation (WHO) recommends expanding surveillance over pathogens, such as RSV and hMPV, through the Mosaic ...
Oliver Martyn   +5 more
wiley   +1 more source

Human Rhinovirus A16 Infection of Mast Cells Promotes T2 and Non‐T2 Immune Responses That Are Modulated by the Airway Epithelium

open access: yes
Allergy, EarlyView.
Ying Lai   +9 more
wiley   +1 more source

Asymptomatic Mycoplasma pneumoniae Infections in Children During a Mycoplasma Outbreak

open access: yesActa Paediatrica, Volume 115, Issue 7, Page 1496-1502, July 2026.
ABSTRACT Aim The aim of this study was to investigate the occurrence of M. pneumoniae detections in asymptomatic children during an outbreak. Methods We prospectively recruited symptomatic and asymptomatic children under 18 years of age between 1 January and 1 November 2024. Picornavirus positivity was also assessed in both groups.
Minna Honkila   +7 more
wiley   +1 more source

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