Results 91 to 100 of about 60,470 (243)
IL-17 Modulation of Rhinovirus-Induced Allergic Airways Disease [PDF]
Asthma is a chronic inflammatory disease of the airways, resulting in significant morbidity and premature deaths. Rhinoviruses, agents of the common cold, have been identified as the most frequent viruses inducing asthma exacerbations.
Peel, Tamlyn Jolyon Robert
core +1 more source
Pseudomonas aeruginosa rhamnolipids stabilize human rhinovirus 14 virions
Many mammalian viruses encounter bacteria and bacterial molecules over the course of infection. Previous work has shown that the microbial ecology of the gut plays an integral role in poliovirus and coxsackievirus infection, where bacterial glycans can ...
Joshua J. Baty +2 more
doaj +1 more source
Viruses exacerbating chronic pulmonary disease: the role of immune modulation
Chronic pulmonary diseases are a major cause of morbidity and mortality and their impact is expected to increase in the future. Respiratory viruses are the most common cause of acute respiratory infections and it is increasingly recognized that ...
Singanayagam Aran +3 more
doaj +1 more source
The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley +1 more source
IgE running interference for rhinovirus?
Anti-IgE treatment in pediatric allergic asthmatics reduces rates of symptomatic rhinovirus infection.
Sarah E. Henrickson
core +1 more source
Modeling Asthma in Mice Using Rhinovirus Infection
Rhinovirus (RV) infection is linked to early life wheezing and exacerbation of adult asthma. RV infection can be modeled in adult and neonatal mice. This chapter outlines methods for the production of standardized human rhinovirus A1B and mouse infection.
Bentley, JK
core +1 more source
Introduction Asthma is a leading cause of morbidity and healthcare use among children. Risk factors of childhood asthma include atopic predisposition and severe wheezing episodes caused by rhinovirus infection in early life.
Maria Vollsæter +21 more
doaj +1 more source
ABSTRACT Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are seasonal respiratory viruses that can cause severe outcomes, particularly in older adults; however, their burden remains under‐captured. The World Health Organisation (WHO) recommends expanding surveillance over pathogens, such as RSV and hMPV, through the Mosaic ...
Oliver Martyn +5 more
wiley +1 more source
Asymptomatic Mycoplasma pneumoniae Infections in Children During a Mycoplasma Outbreak
ABSTRACT Aim The aim of this study was to investigate the occurrence of M. pneumoniae detections in asymptomatic children during an outbreak. Methods We prospectively recruited symptomatic and asymptomatic children under 18 years of age between 1 January and 1 November 2024. Picornavirus positivity was also assessed in both groups.
Minna Honkila +7 more
wiley +1 more source

