Results 81 to 90 of about 77,402 (234)

Severe pertussis infection in infants less than 6 months of age: clinical manifestations and molecular characterization [PDF]

, 2017
We conducted a study to determine the main traits of pertussis among unimmunized infants less than 6 months of age. From August 2012 to March 2015, 141 nasopharyngeal aspirates (NPAs) were collected from infants with respiratory symptoms attending 2
Buttinelli, Gabriele, Carsetti, Rita, Concato, Carlo, Di Mattia, Greta, Fedele, Giorgio, Gesualdo, Francesco, Midulla, Fabio, Nicolai, Ambra, Stefanelli, Paola, the Pertussis Study Group,, Tozzi, Alberto E., Vacca, Paola, Villani, Alberto   +12 more
core   +1 more source

Pathogenesis of rhinovirus infection [PDF]

Current Opinion in Virology, 2012
Since its discovery in 1956, rhinovirus (RV) has been recognized as the most important virus producing the common cold syndrome. Despite its ubiquity, little is known concerning the pathogenesis of RV infections, and some of the research in this area has led to contradictions regarding the molecular and cellular mechanisms of RV-induced illness.
Joshua L, Kennedy, Ronald B, Turner, Thomas, Braciale, Peter W, Heymann, Larry, Borish   +4 more
openaire   +2 more sources

Eccrine Squamous Syringometaplasia Mimicking Acute Cutaneous GVHD in a Pediatric HSCT Recipient: Case Report and Brief Review of the Indexed Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Eccrine squamous syringometaplasia (ESS) is an uncommon reactive alteration of eccrine ducts, most often reported in oncologic and transplant settings, where it may clinically mimic acute cutaneous graft‐versus‐host disease (GVHD). We describe a 3‐year‐old boy with chronic granulomatous disease who developed a diffuse erythematous eruption 6 ...
Benedetta Galli, Cecilia Catapano, Iacopo Ghini, Mariateresa Rossi, Marina Venturini, Valeria Boccaletti   +5 more
wiley   +1 more source

Exploring the Clinical Characteristics and Outcomes of Rhinovirus Infection in Hospitalized Children Compared with Other Respiratory Viruses

Children
Background: Acute viral respiratory tract infections constitute a significant challenge in pediatric healthcare globally, with rhinovirus representing one of the primary etiological agents.
Sigrid Covaci, Claudiu Filimon, Mihai Craiu   +2 more
doaj   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

The FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb, Dominik Hörtnagel, Chris Oostenbrink, Paul G. Furtmüller, Stefan Hofbauer   +4 more
wiley   +1 more source

Antibody Serologies and Diagnostic Considerations in Reactive Infectious Mucocutaneous Eruption

Pediatric Dermatology, EarlyView.
ABSTRACT Reactive infectious mucocutaneous eruption (RIME) is an uncommon, post‐infectious mucocutaneous condition often associated with Mycoplasma pneumoniae, but which can be triggered by other pathogens. We retrospectively reviewed eight young adult patients diagnosed with RIME over a 10‐year period, all of whom had positive Mycoplasma pneumoniae ...
Aaron D. Smith, Olivia Cohen, Peter Jowdy, Catherine E. Lyons, Lauren Yi, Barrett Zlotoff   +5 more
wiley   +1 more source

Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases

Virology Journal, 2004
For two centuries, vaccination has been the dominating approach to develop prophylaxis against viral infections through immunological prevention. However, vaccines are not always possible to make, are ineffective for many viral infections, and also carry
Le Calvez Hervé, Yu Mang, Fang Fang
doaj   +1 more source

Minimum energy paths for conformational changes of viral capsids [PDF]

, 2017
In this work we study how a viral capsid can change conformation using techniques of Large Deviations Theory for stochastic differential equations. The viral capsid is a model of a complex system in which many units - the proteins forming the capsomers -
Cermelli, Paolo, Indelicato, Giuliana, Zappa, Emilio   +2 more
core   +2 more sources

Infection Complications in Pediatric Patients With Inborn Errors of Immunity After Umbilical Cord Blood Transplantation: A Chinese Single‐Center Study

Transplant Infectious Disease, EarlyView.
This study reveals that infections are highly prevalent in pediatric IEI patients after umbilical cord blood transplantation, with early‐stage infections and bloodstream infections strongly associated with poorer survival. These findings advocate for risk‐stratified surveillance and preemptive strategies in high‐risk subgroups.
Zhongling Wei, Ping Wang, Wenjin Jiang, Jie Man, Ying Huang, Xiaochuan Wang, Hongsheng Wang, Xiaowen Qian, Xiaowen Zhai   +8 more
wiley   +1 more source

Lethal Respiratory Disease Associated with Human Rhinovirus C in Wild Chimpanzees, Uganda, 2013

Emerging Infectious Diseases, 2018
We describe a lethal respiratory outbreak among wild chimpanzees in Uganda in 2013 for which molecular and epidemiologic analyses implicate human rhinovirus C as the cause.
Erik J. Scully, Sarmi Basnet, Richard W. Wrangham, Martin N. Muller, Emily Otali, David Hyeroba, Kristine A. Grindle, Tressa E. Pappas, Melissa Emery Thompson, Zarin Machanda, Kelly E. Watters, Ann C. Palmenberg, James E. Gern, Tony L. Goldberg   +13 more
doaj   +1 more source