Results 1 to 10 of about 52,817 (240)
RhoA Signaling in Neurodegenerative Diseases [PDF]
Cells, 2022 Ras homolog gene family member A (RhoA) is a small GTPase of the Rho family involved in regulating multiple signal transduction pathways that influence a diverse range of cellular functions.
Sissel Ida Schmidt +3 more
doaj +5 more sources
Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling. [PDF]
PLoS Biology, 2020 The small GTPase RhoA is a central signaling enzyme that is involved in various cellular processes such as cytoskeletal dynamics, transcription, and cell cycle progression.
Jason Z Zhang +5 more
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RhoA Regulation of Cardiomyocyte Differentiation [PDF]
The Scientific World Journal, 2013 Earlier findings from our laboratory implicated RhoA in heart developmental processes. To investigate factors that potentially regulate RhoA expression, RhoA gene organisation and promoter activity were analysed.
Mari Kaarbø +2 more
doaj +4 more sources
RhoA Is a Crucial Regulator of Myoblast Fusion
Cells, 2023 Satellite cells (SCs) are adult muscle stem cells that are mobilized when muscle homeostasis is perturbed. Here we show that RhoA in SCs is indispensable to have correct muscle regeneration and hypertrophy.
Chiara Noviello +6 more
doaj +4 more sources
口腔疾病防治, 2023 Objective To investigate the effect of isoprene cysteine carboxymethyltransferase (ICMT) gene on the migration and invasion of salivary adenoid cystic cancer cells (SACC) and the related mechanism, to provide experimental evidence for molecular targeted ...
LU Zhou +3 more
doaj +1 more source
Di-san junyi daxue xuebao, 2021 Objective To explore the role and underlying mechanism of heat shock protein 27 (HSP27) in bladder smooth muscle remodeling after bladder outlet obstruction (BOO).
LIAO Deyang +5 more
doaj +1 more source
Small GTPases, 2013 Mechanical forces influence nearly all aspects of biology. Cells are equipped with numerous mechanosensitive proteins that activate various signaling cascades in response to mechanical cues from their environment. Much interest lies in understanding how cells respond to external stresses.
Caitlin, Collins, Ellie, Tzima
openaire +2 more sources
Frontiers in Bioscience-Landmark, 2021 Background: Cystic fibrosis transmembrane conductance regulator (CFTR) has been associated with vascular tone and blood pressure (BP), however, its role in the genesis of hypertension remains elusive.
Liyan Zhao +8 more
doaj +1 more source
Cells, 2020 Vascular smooth muscle cells (VSMCs) are the predominant cell type in the blood vessel wall. Changes in VSMC actomyosin activity and morphology are prevalent in cardiovascular disease. The actin cytoskeleton actively defines cellular shape and the LInker
Lauren Porter +12 more
doaj +1 more source
Exosomal Dvl3 promoted the aggressive phenotypic transformation of RA-FLS via wnt pathway
Autoimmunity, 2022 Objective This study was performed to explore the function and mechanism of Dvl3 in RA-FLS by exosome intervention. Methods The expression pattern of Dvl3 was examined by IHC, WB, and qPCR.
Weixing Tan +8 more
doaj +1 more source