Results 201 to 210 of about 123,069 (394)
RhoA/Rock2/Limk1/cofilin1 pathway is involved in attenuation of neuronal dendritic spine loss by paeonol in the frontal cortex of D-galactose and aluminum-induced Alzheimer’s disease-like rat model [PDF]
, 2020 Fei Han +8 more
openalex +1 more source
Unlocking Financial Inclusion: The Dynamics of Bank Account Ownership in Urban Slums
Sustainable Development, EarlyView.ABSTRACT Financial inclusion is a key driver of sustainable development, contributing to poverty reduction (SDG 1), gender equality (SDG 5), and reduced inequalities (SDG 10). Despite extensive financial‐inclusion policies in India, residents of urban slums remain largely excluded from formal banking systems.
Davide Moro +3 more
wiley +1 more source
UroPrecision, EarlyView.ABSTRACT Holmium laser enucleation of the prostate (HoLEP) has emerged as a widely adopted surgical technique for the management of benign prostatic hyperplasia (BPH), regardless of prostate size; however, its impact on male sexual function—particularly in terms of erectile and ejaculatory outcomes—remains a subject of ongoing debate.
Muhammed Arif İbiş +5 more
wiley +1 more source
S1PR3/RhoA signaling pathway in microglia mediates inflammatory activation in early brain injury after subarachnoid hemorrhage [PDF]
Lu Feng +5 more
openalex +1 more source
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases. [PDF]
, 2002 We show here the transient activation of the small GTPase Rac, followed by a rise in reactive oxygen species (ROS), as necessary early steps in a signal transduction cascade that lead to NFkappaB activation and collagenase-1 (CL-1)/matrix ...
Werb, Zena, Werner, Erica
core
VIEW, EarlyView.In this study, we constructed a prognostic model for ccRCC patients treated with Sunitinib through a deep learning‐based multimodal approach. Our CGPR model further confirms the feasibility of integrating multimodal and provides guidance for future tumor patients to receive precision therapy.
Xi Tian +11 more
wiley +1 more source
Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis
Allergy, EarlyView.This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino +12 more
wiley +1 more source
System level network data and models attack cancer drug resistance
British Journal of Pharmacology, EarlyView.Drug resistance is responsible for >90% of cancer related deaths. Cancer drug resistance is a system level network phenomenon covering the entire cell. Small‐scale interactomes and signalling network models of drug resistance guide directed drug development.
Márk Kerestély +6 more
wiley +1 more source