Results 1 to 10 of about 2,906 (266)

Gentle Rhodamines for Live-Cell Fluorescence Microscopy [PDF]

open access: yesACS Central Science
Rhodamines have been continuously optimized in brightness, biocompatibility, and color to fulfill the demands of modern bioimaging. However, the problem of phototoxicity caused by the excited fluorophore under long-term illumination has been largely ...
Tianyan Liu   +16 more
doaj   +3 more sources

Radiolabeled Silicon-Rhodamines as Bimodal PET/SPECT-NIR Imaging Agents

open access: yesPharmaceuticals, 2021
Radiolabeled fluorescent dyes are decisive for bimodal imaging as well as highly in demand for nuclear- and optical imaging. Silicon-rhodamines (SiRs) show unique near-infrared (NIR) optical properties, large quantum yields and extinction coefficients as
Thines Kanagasundaram   +2 more
exaly   +4 more sources

In vivo nerve-specificity of rhodamines and Si-rhodamines [PDF]

open access: yesMolecular-Guided Surgery: Molecules, Devices, and Applications VI, 2020
Accidental nerve damage or transection of vital nerve structures remains an unfortunate reality that is often associated with surgery. Despite the existence of nerve-sparing techniques, the success of such procedures is not only complicated by anatomical variance across patients but is also highly dependent on a surgeon's first-hand experience that is ...
K. A. Sashini U. Kumarapeli   +5 more
core   +3 more sources

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery [PDF]

open access: yesAdvanced Science
Fluorescence‐guided surgery is an emerging clinical field that aims to improve cancer detection in real‐time, enabling spot‐on therapeutic decisions. The use of fluorescent affinity probes has primarily involved systemically injected probes and, more ...
Zachary Rabinowitz   +2 more
doaj   +2 more sources

Efforts toward PET-Activatable Red-Shifted Silicon Rhodamines and Silicon Pyronine Dyes

open access: yesPharmaceuticals, 2023
Tracers for bimodal optical imaging and positron emission tomography unite multiple advantages in a single molecule. Their tumor-specific uptake can be visualized after their PET activation by radiofluorination via PET/CT or PET/MRI allowing for staging ...
Carsten Sven Kramer   +3 more
doaj   +2 more sources

A Contrastive-Learning-Based Pre-Training Framework for Optical Property Prediction of Low-Data Rhodamines with Interpretable Multitask Graph Neural Networks [PDF]

open access: yesMolecules
Accurate prediction of maximum absorption (λabs) and emission (λemi) wavelengths are essential for the design of high-performance rhodamine probes. However, available rhodamine optical data is extremely limited and heterogeneous, posing challenges for ...
Jiangguo Qiu   +5 more
doaj   +2 more sources

New Fluorinated Rhodamines for Optical Microscopy and Nanoscopy [PDF]

open access: yesChemistry - A European Journal, 2010
New photostable rhodamine dyes represented by the compounds 1 a-r and 3-5 are proposed as efficient fluorescent markers with unique combination of structural features.
Gyuzel Y Mitronova   +2 more
exaly   +2 more sources

A new approach to silicon rhodamines by Suzuki–Miyaura coupling – scope and limitations

open access: yesBeilstein Journal of Organic Chemistry, 2019
Background: Silicon rhodamines are of particular interest because of their advantageous dye properties (fluorescence- and biostability, quantum efficiency, tolerance to photobleaching).
Thines Kanagasundaram   +2 more
exaly   +2 more sources

Fluorescent Rhodamines and Fluorogenic Carbopyronines for Super‐Resolution STED Microscopy in Living Cells

open access: yesAngewandte Chemie - International Edition, 2016
A range of bright and photostable rhodamines and carbopyronines with absorption maxima in the range of =500-630nm were prepared, and enabled the specific labeling of cytoskeletal filaments using HaloTag technology followed by staining with 1m solutions ...
Alexey N Butkevich   +2 more
exaly   +4 more sources

Fluorescent Dyes in Hydrological Tracing: Application Methods, Ecotoxicological Effects, and Safe Application Levels [PDF]

open access: yesJournal of Xenobiotics
Fluorescent dyes are commonly used as tracers in hydrological investigations to quantify transport pathways, residence times, mixing behavior, and connectivity in surface water, groundwater, and coastal systems. Despite their long history of application,
Carlos J. A. Campos   +3 more
doaj   +2 more sources

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