Results 61 to 70 of about 4,220 (277)

Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges

open access: yesAdvanced Functional Materials, EarlyView.
Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley   +1 more source

Chemical derivatization strategies for enhancing the HPLC analytical performance of natural active triterpenoids

open access: yesJournal of Pharmaceutical Analysis
Triterpenoids widely exist in nature, displaying a variety of pharmacological activities. Determining triterpenoids in different matrices, especially in biological samples holds great significance. High-performance liquid chromatography (HPLC) has become
Xiao-Feng Huang   +5 more
doaj   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

open access: yesAdvanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal   +9 more
wiley   +1 more source

Free Radical Shadow Cure Initiated Using Two-Component and Three-Component Initiator Systems [PDF]

open access: yes, 2012
In photopolymerization systems, “shadow cure” may be defined as polymerization which extends into regions which are not illuminated by the incident initiating light source.
Alec B. Scranton   +2 more
core   +1 more source

Mechanochromism of Glassy Polymers Enabled by a Loop‐Forming Supramolecular Mechanophore

open access: yesAdvanced Functional Materials, EarlyView.
The supramolecular mechanophore LOOP is covalently introduced into glassy polymers, capable of reporting force‐induced pre‐failure damage and local fracture events in polymer glasses. Under different mechanical deformation modes, including grinding, tensile stretching, and scratching, LOOP probes irreversible events in polymer glasses through a ...
Linlin Deng   +6 more
wiley   +1 more source

Understanding the AIE phenomenon of nonconjugated rhodamine derivatives via aggregation-induced molecular conformation change

open access: yesNature Communications
The bottom-up molecular science research paradigm has greatly propelled the advancement of materials science. However, some organic molecules can exhibit markedly different properties upon aggregation.
Lin-Lin Yang   +10 more
doaj   +1 more source

Mechanisms of remanent optical alignment of dyes in a gel matrix

open access: yes, 1996
International audienceWe present the mechanisms of a remanent alignment of polarizable molecules dispersed in a solid silica gel matrix, when submitted to powerful, femtosecond, linearly polarized, optical pulses emitted from a dye laser.
Bentivegna, Florian   +4 more
core   +4 more sources

Fluorescent labeling of plasmid DNA and mRNA : gains and losses of current labeling strategies [PDF]

open access: yes, 2016
Live-cell imaging has provided the life sciences with insights into the cell biology and dynamics. Fluorescent labeling of target molecules proves to be indispensable in this regard. In this Review, we focus on the current fluorescent labeling strategies
Rombouts, Koen   +2 more
core   +1 more source

A novel pH probe based on a rhodamine–rhodamine platform

open access: yesRSC Adv., 2014
A novel pH probe based on rhodamine–rhodanine platform.
Xuan-Xuan Zhao   +9 more
openaire   +1 more source

Home - About - Disclaimer - Privacy