Results 61 to 70 of about 582 (222)

S‐Nitrosothiols as Thiol‐Protecting Groups for Controlled Thiol‐Maleimide Crosslinking of Homogeneous Soft Hydrogels

Advanced Materials, EarlyView.
Rapid thiol‐maleimide addition frequently outpaces mixing, resulting in heterogeneous hydrogels. S‐nitrosothiols act as thiol‐protecting groups, allowing uniform mixing with maleimide‐functionalized polymers before gelation. Sodium thiosulfate or sodium ascorbate then regenerates thiols on demand, triggering controlled thiol‐maleimide crosslinking ...
Julian A. Serna, Michelle J. Iwohn, Maximilian Seifermann, Stefan Heißler, Maike Schliephake, Franziska Dopp, Claudia Muhle‐Goll, Pavel A. Levkin   +7 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Understanding the AIE phenomenon of nonconjugated rhodamine derivatives via aggregation-induced molecular conformation change

Nature Communications
The bottom-up molecular science research paradigm has greatly propelled the advancement of materials science. However, some organic molecules can exhibit markedly different properties upon aggregation.
Lin-Lin Yang, Haoran Wang, Jianyu Zhang, Bo Wu, Qiyao Li, Jie-Ying Chen, A-Ling Tang, Jacky W. Y. Lam, Zheng Zhao, Song Yang, Ben Zhong Tang   +10 more
doaj   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Fluorescent Dyes in Hydrological Tracing: Application Methods, Ecotoxicological Effects, and Safe Application Levels

Journal of Xenobiotics
Fluorescent dyes are commonly used as tracers in hydrological investigations to quantify transport pathways, residence times, mixing behavior, and connectivity in surface water, groundwater, and coastal systems. Despite their long history of application,
Carlos J. A. Campos, Louis A. Tremblay, Olivier Champeau, Gregory Goblick   +3 more
doaj   +1 more source

Decoding Synergistic Pathways in Bimetallic MOFs for Advanced Oxidation Processes

Advanced Materials, EarlyView.
This review presents a unified framework linking metal pairing and framework design with electronic structure, redox cycling, oxidant activation, reactive‐species generation, and catalytic performance across photocatalytic and oxidant‐based BMOF‐AOPs. The resulting design principles guide the development of hydrolytically stable and efficient BMOFs for
Karim El‐Naggar, Huayang Zhang, Shaobin Wang   +2 more
wiley   +1 more source

A practical CO2-mediated synthesis of 5,6-carboxylated silicon-rhodamines for targeted probe development

Beilstein Journal of Organic Chemistry
Silicon-rhodamine (SiR) dyes are among the most important fluorophores for super-resolution imaging owing to their far-red emission, high photostability, and tunable lactone–zwitterion equilibrium.
Dongjie Hou, Shaowei Wu, Ning Xu, Pengjun Bao, Wenhao Jia, Qinglong Qiao, Zhaochao Xu   +6 more
doaj   +1 more source

A Contrastive-Learning-Based Pre-Training Framework for Optical Property Prediction of Low-Data Rhodamines with Interpretable Multitask Graph Neural Networks

Molecules
Accurate prediction of maximum absorption (λabs) and emission (λemi) wavelengths are essential for the design of high-performance rhodamine probes. However, available rhodamine optical data is extremely limited and heterogeneous, posing challenges for ...
Jiangguo Qiu, Yanling Wu, Hong Zhang, Menglong Li, Xuemei Pu, Yanzhi Guo   +5 more
doaj   +1 more source

Elasticity‐Driven Periodic Polarization Patterns in a Chiral Ferroelectric Nematic Fluid

Advanced Materials, EarlyView.
Chiral polar ferroelectric nematic fluids exhibit spontaneous formation of stripe, square, and hexagonal polarization textures under confinement. Controlled by thickness and anchoring, these patterns produce spatially modulated nonlinear optical responses.
Anej Sterle, Peter Medle Rupnik, Luka Cmok, Aitor Erkoreka, Marta Lavrič, Natan Osterman, Calum J. Gibb, Jordan Hobbs, Josu Martinez‐Perdiguero, Richard J. Mandle, Alenka Mertelj, Nerea Sebastián   +11 more
wiley   +1 more source

Combinatorial approach for development of optical gas sensors - concept and application of high-throughput experimentation [PDF]

, 2005
This work describes the combinatorial approach to development of optical gas sensors. Methods and instruments for the high throughput preparation and characterisation of polymer-based optical sensors are presented.
Apostolidis, Athanasios
core   +1 more source