Results 81 to 90 of about 6,777 (246)

Gut Microbiota–Derived Metabolites as Potential Therapeutics in Mitochondrial Dysfunction‐Driven Intestinal Inflammatory Diseases

Cellular Microbiology, Volume 2025, Issue 1, 2025.
Inflammatory bowel diseases are a group of chronic diseases with increasing global incidence and rising morbidity and mortality, contributing to a significant health burden. Mainstream treatments for IBD are focused on controlling inflammation and alleviating the symptoms, also aiming for intestinal barrier repair.
Gayatri Reghu, Pardhipa Nandigam, Ashna Fathima, Trinath Jamma, Suraiya Saleem   +4 more
wiley   +1 more source

The Periplasmic Chaperone Network of Campylobacter jejuni: Evidence that SalC (Cj1289) and PpiD (Cj0694) Are Involved in Maintaining Outer Membrane Integrity [PDF]

, 2017
The outer membrane (OM) of Gram-negative pathogenic bacteria is a key structure in host–pathogen interactions that contains a plethora of proteins, performing a range of functions including adhesion, nutrient uptake, export of effectors and interaction ...
Asakura, Baek, Behrens, Boehm, Bos, Brøndsted, Cameron, Dartigalongue, Denoncin, Elmi, Elmi, Ge, Gibson, Guccione, Hitchcock, Hoy, Ideno, Kale, Karlyshev, Leon-Kempis Mdel, Lipinska, Mahdavi, Matern, Moors, Mücke, Novik, Obi, O’Brien, Pace, Rathbun, Rathbun, Riddle, Rizzitello, Rubinchik, Rudd, Sachelaru, Saint-Cyr, Scholz, Sheppard, Sklar, Stymest, Tapia-Pastrana, Tribble, Wang, Weininger, Wu   +45 more
core   +2 more sources

Role of hydrogen sulfide in health and disease

MedComm, Volume 5, Issue 9, September 2024.
Abstract In the past, hydrogen sulfide (H2S) was recognized as a toxic and dangerous gas; in recent years, with increased research, we have discovered that H2S can act as an endogenous regulatory transmitter. In mammals, H2S‐catalyzing enzymes, such as cystathionine‐β‐synthase, cystathionine‐γ‐lyase, and 3‐mercaptopyruvate sulfurtransferase, are ...
Yu‐Qing Jin, Hang Yuan, Ya‐Fang Liu, Yi‐Wen Zhu, Yan Wang, Xiao‐Yi Liang, Wei Gao, Zhi‐Guang Ren, Xin‐Ying Ji, Dong‐Dong Wu   +9 more
wiley   +1 more source

Effects of the Gut microbiota on Amygdalin and its use as an anti-cancer therapy: Substantial review on the key components involved in altering dose efficacy and toxicity

Biochemistry and Biophysics Reports, 2018
Conventional and Alternative Medicine (CAM) is popularly used due to side-effects and failure of approved methods, for diseases like Epilepsy and Cancer.
Vani Jaswal, Jeyanthi Palanivelu, Ramalingam C, Dr   +2 more
doaj   +1 more source

An Expanded Mechanism for Rhodanese Catalysis

Journal of Biological Chemistry, 1974
Abstract The kinetic behavior of rhodanese (thiosulfate:cyanide sulfurtransferase, EC 2.8.1.1) was investigated at pH values from 5.0 to 10.8. The binding of thiosulfate was shown to be dependent upon a pK' of 9.9, with the protonated enzyme binding the substrate much more strongly than the deprotonated form. An enzymic nucleophile displaces sulfite to
P, Schlesinger, J, Westley
openaire   +2 more sources

Redox signaling via the molecular chaperone BiP protects cells against endoplasmic reticulum-derived oxidative stress [PDF]

, 2014
Oxidative protein folding in the endoplasmic reticulum (ER) has emerged as a potentially significant source of cellular reactive oxygen species (ROS).
Kaiser, Chris, Pareja, Kristeen A, Sevier, Carolyn S, Wang, Jie   +3 more
core   +1 more source

GpEF1A: a novel lysine methyltransferase gene from Gypsophila perfoliata L. involved in boron homeostasis

Plant Biology, Volume 26, Issue 5, Page 727-734, August 2024.
Yeast functional screening identified GpEF1A from Gypsophila perfoliata potentially to be utilized to generate B stress‐tolerant plants. Abstract Rapid accumulation of boron (B) leads to toxicity in plant tissues, and the narrow gap between deficiency and toxicity makes it difficult to adjust essential B levels in soil for plant productivity. Therefore,
M. A. Akbudak, N. Cirik, S. N. Erdeger, E. Filiz, S. Dogu, M. Bor   +5 more
wiley   +1 more source

Enzymes as Biomarkers of Environmental Stress in African Catfish (Clarias gariepinus) in Osun State, Nigeria

Journal of Health and Pollution, 2017
Background. Many natural aquatic bodies have been contaminated with heavy metals released from domestic, industrial and other anthropogenic activities.
Omolara Titilayo Aladesanmi, Femi Kayode Agboola, Rapheal Emuebe Okonji   +2 more
doaj   +1 more source

Die Funktion des Responseregulators ARR2 in der Entwicklung von Arabidopsis thaliana [PDF]

, 2004
In dieser Arbeit konnte mittels physiologischer Experimente, Expressionsanalysen, Phosphorylierungsassays und Transaktivierungsanalysen eine komplexe Funktion von ARR2 in verschiedenen Signaltransduktionswegen von Arabidopsis aufgedeckt werden.
Haß, Claudia
core  

Ribosomal dormancy at the nexus of ribosome homeostasis and protein synthesis

BioEssays, Volume 46, Issue 7, July 2024.
Both prokaryotes and eukaryotes possess multiple forms of dormant ribosomes under unfavorable conditions. Dormancy factors act as translation repressors by occupying functionally crucial ribosomal sites. Dormancy factors protect the ribosomes from the degradation pathways.
Saloni Koli, Sunil Shetty
wiley   +1 more source