Results 51 to 60 of about 2,705 (179)
ABSTRACT Background Dermatophyte infections, which are among the most prevalent fungal infections globally, affect skin, hair and nails, accounting for significant morbidity. Epidemiological data on dermatophytosis in the UK are limited. One notable study in 2007 provided insights into the causative agents of dermatophyte infections in the UK; however,
Khanh Linh Phan, David J. Chandler
wiley +1 more source
Summary Background Clothing in human medical environments has been shown to be contaminated with micro‐organisms. There is little work in this area in the veterinary environment and none in equine veterinary environments. Objectives To characterise microbial contamination of veterinary clothing throughout a work shift in an equine hospital. The pattern
M. Bennett, T. Cogan, V. Roberts
wiley +1 more source
Virulence-associated plasmids in Rhodococcus equi [PDF]
Twenty-three strains of Rhodococcus equi from independent clinical cases were analyzed for the presence of virulence plasmid DNA. Of the clinical isolates, 19 contained an 85-kb plasmid and the remaining 4 contained a 90-kb plasmid. All of the isolates expressed 15- to 17-kDa antigens and were virulent in mice.
S, Takai +7 more
openaire +2 more sources
Antibiotic use has been linked to changes in the population structure of human pathogens and the clonal expansion of multidrug-resistant (MDR) strains among healthcare- and community-acquired infections.
Sonsiray Álvarez-Narváez +5 more
doaj +1 more source
Introduction We describe cases of contamination of Mycobacterium ulcerans infections (Buruli ulcer) with Rhodococcus erythropolis, a bacterium of environmental origin that is rarely associated with human infection. Case Presentation The infectious pathogen of Buruli ulcer, Mycobacterium ulcerans, was detected and cultured in vitro from two lesion swabs
Francis Zeukeng +9 more
wiley +1 more source
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source
Rhodococcus equi:An Emerging Pathogen [PDF]
More than 100 cases of Rhodococcus equi infection have been reported since the first description of human disease caused by this organism. The vast majority of patients infected with R. equi are immunocompromised, and two-thirds have human immunodeficiency virus infection. The clinical manifestations of R.
David M, Weinstock, Arthur E, Brown
openaire +2 more sources
The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.
We report the genome of the facultative intracellular parasite Rhodococcus equi, the only animal pathogen within the biotechnologically important actinobacterial genus Rhodococcus. The 5.0-Mb R.
Michal Letek +23 more
doaj +1 more source
Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer +6 more
wiley +1 more source

