Results 81 to 90 of about 33,261 (220)
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
Drug Development Research, Volume 86, Issue 8, December 2025.ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source
Rhodococcus equi:An Emerging Pathogen [PDF]
Clinical Infectious Diseases, 2002 More than 100 cases of Rhodococcus equi infection have been reported since the first description of human disease caused by this organism. The vast majority of patients infected with R. equi are immunocompromised, and two-thirds have human immunodeficiency virus infection. The clinical manifestations of R.
David M, Weinstock, Arthur E, Brown
openaire +2 more sources
Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines
eJHaem, Volume 6, Issue 6, December 2025.ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer +6 more
wiley +1 more source
Antimicrobial prescribing guidelines for horses in Australia
Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt +18 more
wiley +1 more source
The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.
PLoS Genetics, 2010 We report the genome of the facultative intracellular parasite Rhodococcus equi, the only animal pathogen within the biotechnologically important actinobacterial genus Rhodococcus. The 5.0-Mb R.
Michal Letek +23 more
doaj +1 more source
Antimicrobial Resistance in Rhodococcus equi
Microbiology Spectrum, 2017 ABSTRACT Pneumonia caused by Rhodococcus equi remains an important cause of disease and death in foals. The combination of a macrolide (erythromycin, azithromycin, or clarithromycin) with rifampin has been the recommended treatment for foals with clinical signs of infection caused by R. equi
Steeve, Giguère +2 more
openaire +2 more sources
Tear Film Osmolarity in Horses With Bacterial Conjunctivitis
Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.This study evaluated tear film osmolarity in horses with bacterial conjunctivitis. Although osmolarity values were higher in affected horses compared to healthy ones, the difference was not statistically significant. These findings highlight the need for further research before tear osmolarity can be considered a reliable diagnostic marker in equine ...
Ahad Saberinia +2 more
wiley +1 more source
Revista Portuguesa de Pneumologia, 2007 A infecção humana por Rhodococcus equi, mesmo no contexto da infecção pelo VIH, é relativamente rara. Os autores apresentam o caso clínico de um indivíduo, infectado pelo VIH, que apresentava um quadro clínico e imagiológico compatível com pneumonia ...
Paula Esteves +3 more
doaj
Oral Administration of Electron-Beam Inactivated Rhodococcus equi Failed to Protect Foals against Intrabronchial Infection with Live, Virulent R. equi. [PDF]
PLoS ONE, 2016 There is currently no licensed vaccine that protects foals against Rhodococcus equi-induced pneumonia. Oral administration of live, virulent R. equi to neonatal foals has been demonstrated to protect against subsequent intrabronchial challenge with ...
Joana N Rocha +9 more
doaj +1 more source