Results 11 to 20 of about 3,227 (159)

Improvement of Biocatalytic Properties and Cytotoxic Activity of L-Asparaginase from Rhodospirillum rubrum by Conjugation with Chitosan-Based Cationic Polyelectrolytes [PDF]

Pharmaceuticals, 2022
L-asparaginases (L-ASNases, EC 3.5.1.1) are a family of enzymes that are widely used for the treatment of lymphoblastic leukemias. L-ASNase from Rhodospirillum rubrum (RrA) has a low molecular weight, low glutaminase activity, and low immunogenicity ...
Natalia V. Dobryakova, Dmitry D. Zhdanov, Nikolay N. Sokolov, Svetlana S. Aleksandrova, Marina V. Pokrovskaya, Elena V. Kudryashova   +5 more
doaj   +2 more sources

H⁺-Translocating Membrane-Bound Pyrophosphatase from Rhodospirillum rubrum Fuels Escherichia coli Cells via an Alternative Pathway for Energy Generation [PDF]

Microorganisms, 2023
Inorganic pyrophosphatases (PPases) catalyze an essential reaction, namely, the hydrolysis of PPi, which is formed in large quantities as a side product of numerous cellular reactions.
Evgeniya A. Malykh, Liubov I. Golubeva, Ekaterina S. Kovaleva, Mikhail S. Shupletsov, Elena V. Rodina, Sergey V. Mashko, Nataliya V. Stoynova   +6 more
doaj   +2 more sources

Investigation of candidate genes involved in the rhodoquinone biosynthetic pathway in Rhodospirillum rubrum. [PDF]

PLoS ONE, 2019
The lipophilic electron-transport cofactor rhodoquinone (RQ) facilitates anaerobic metabolism in a variety of bacteria and selected eukaryotic organisms in hypoxic environments.
Amanda R M Campbell, Benjamin R Titus, Madeline R Kuenzi, Fernando Rodriguez-Perez, Alysha D L Brunsch, Monica M Schroll, Matthew C Owen, Jeff D Cronk, Kirk R Anders, Jennifer N Shepherd   +9 more
doaj   +2 more sources

The metabolic pathways of carbon assimilation and polyhydroxyalkanoate production by Rhodospirillum rubrum in response to different atmospheric fermentation. [PDF]

PLoS ONE
The purple nonsulfur bacteria, Rhodospirillum rubrum, is recognized as a potential strain for PHAs bioindustrial processes since they can assimilate a broad range of carbon sources, such as syngas, to allow reduction of the production costs.
Manyu Tang, Xin Zhen, Guoqiang Zhao, Shuang Wu, Wei Hua, Jingwen Qiang, Cheng Yanling, Wanqing Wang   +7 more
doaj   +2 more sources

Global Proteomic Analysis Reveals High Light Intensity Adaptation Strategies and Polyhydroxyalkanoate Production in Rhodospirillum rubrum Cultivated With Acetate as Carbon Source [PDF]

Frontiers in Microbiology, 2020
Purple non-sulfur bacteria (PNSBs) are well known for their metabolic versatility. Among them, Rhodospirillum rubrum can assimilate a broad range of carbon sources, including volatile fatty acids (VFAs), such as acetate, propionate or butyrate.
Guillaume Bayon-Vicente, Ruddy Wattiez, Baptiste Leroy   +2 more
doaj   +2 more sources

Cryomicroneedle delivery of nanogold-engineered Rhodospirillum rubrum for photochemical transformation and tumor optical biotherapy [PDF]

Bioactive Materials
Tumor metabolite regulation is intricately linked to cancer progression. Because lactate is a characteristic metabolite of the tumor microenvironment (TME), it supports tumor progression and drives immunosuppression.
Qingxia Shi, Ting Yin, Cuiping Zeng, Hong Pan, Ze Chen, Lin Wang, Bo Wang, Mingbin Zheng, Lintao Cai   +8 more
doaj   +2 more sources

Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from Rhodospirillum rubrum to Inhibit Telomerase [PDF]

Pharmaceuticals, 2020
The anticancer effect of L-asparaginases (L-ASNases) is attributable to their ability to hydrolyze L-asparagine in the bloodstream and cancer cell microenvironment.
Anna A. Plyasova, Marina V. Pokrovskaya, Olga M. Lisitsyna, Vadim S. Pokrovsky, Svetlana S. Alexandrova, Abdullah Hilal, Nikolay N. Sokolov, Dmitry D. Zhdanov   +7 more
doaj   +2 more sources

Gene expression analysis reveals distinct PHB depolymerization mechanisms and broader involvement of the PHB cycle in Rhodospirillum rubrum growing on acetate and fructose [PDF]

Microbial Cell Factories
Background Rhodospirillum rubrum owns a dynamic poly(3-hydroxybutyrate) (PHB) cycle: During growth PHB is accumulated and subsequently degraded under carbon starvation. Interestingly, this cycle is typically found for acetate grown R.
Hugo Fleuriot-Blitman, Katerina Sabatova, Véronique Amstutz, Marketa Jakubickova, Eva Slaninova, Katerina Mrazova, María Celeste Ferrín Mendoza, Kamila Hrubanova, Vladislav Krzyzanek, Stanislav Obruca, Karel Sedlar, Manfred Zinn   +11 more
doaj   +2 more sources

Tailor‐made PAT platform for safe syngas fermentations in batch, fed‐batch and chemostat mode with Rhodospirillum rubrum [PDF]

Microbial Biotechnology, 2017
Summary Recently, syngas has gained significant interest as renewable and sustainable feedstock, in particular for the biotechnological production of poly([R]‐3‐hydroxybutyrate) (PHB).
Stephanie Karmann, Stéphanie Follonier, Daniel Egger, Dirk Hebel, Sven Panke, Manfred Zinn   +5 more
doaj   +2 more sources

Metabolic Regulation as a Consequence of Anaerobic 5-Methylthioadenosine Recycling in Rhodospirillum rubrum [PDF]

mBio, 2016
Rhodospirillum rubrum possesses a novel oxygen-independent, aerobic methionine salvage pathway (MSP) for recycling methionine from 5-methylthioadenosine (MTA), the MTA-isoprenoid shunt.
Justin A. North, Jaya Sriram, Karuna Chourey, Christopher D. Ecker, Ritin Sharma, John A. Wildenthal, Robert L. Hettich, F. Robert Tabita   +7 more
doaj   +2 more sources