Results 141 to 150 of about 1,236,122 (386)
The Pace of Aesthetic Process: A Comparative Approach [PDF]
Traditionally, western theory of art has been equipped with a set of dualisms such as subject-object, artistic process-artistic product, active artist-passive spectator, that has supposed a rejection of a plenary notion of the human integrated with ...
Luque Moya, Gloria
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The upregulation of PFKM activates glycolysis, thereby enhancing lactate production in atrial tissue. Atrial lactate accumulation promotes global lactylation and H3K18 lactylation in atrial fibroblasts. P300‐mediated H3K18 lactylation up‐regulates TGF‐β1 transcription, leading to fibroblast activation and thereby contributing to atrial fibrosis.
Ning Fang+15 more
wiley +1 more source
Atrial fibrillation (AF) is associated with exercise intolerance, stroke, and all-cause mortality. However, whether this can be solely attributable to the arrhythmia itself or alternative mechanisms remains controversial.
Jonathan P. Ariyaratnam, MB, BChir+5 more
doaj
THE INFLUENCE OF CORTISONE UPON THE DIURNAL RHYTHM OF RENAL EXCRETORY FUNCTION [PDF]
Jack D. Rosenbaum+3 more
openalex +1 more source
Integrative Approach - New Level Knowledge of Functions: Opportunities and Prospects [PDF]
In this article, the example of the mechanisms of heart rhythmogenesis in the intact organism is used to demonstrate the new capabilities provided by an integrative approach. It is shown that the rhythm is formed in the brain, transmitted to the heart in
Vladimir M. Pokrovskii
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Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
A Touch Enabled Hemodynamic and Metabolic Monitor
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi+19 more
wiley +1 more source