Results 231 to 240 of about 74,231 (262)
Some of the next articles are maybe not open access.
Clinics in Liver Disease, 2009
Ribavirin is ineffective against hepatitis C virus as mono-therapy but is critical in attaining both early virologic response and sustained virologic response when combined with pegylated interferon. Ribavirin has significant dose-limiting toxicities, the most important of which is hemolytic anemia.
William W, Shields, Paul J, Pockros
openaire +2 more sources
Ribavirin is ineffective against hepatitis C virus as mono-therapy but is critical in attaining both early virologic response and sustained virologic response when combined with pegylated interferon. Ribavirin has significant dose-limiting toxicities, the most important of which is hemolytic anemia.
William W, Shields, Paul J, Pockros
openaire +2 more sources
Hemoglobinuria With Ribavirin Treatment
Journal of Clinical Gastroenterology, 2003Chronic hepatitis C virus is a major worldwide cause of hepatitis, cirrhosis, end-stage liver disease, and hepatocellular carcinomas. Combination therapy of ribavirin with short- or long-acting interferon-alpha is now the standard treatment of chronic hepatitis C. This therapy is associated with a wide range of side effects.
Omar Massoud +2 more
openaire +2 more sources
Drug Intelligence & Clinical Pharmacy, 1984
Despite the plethora of antibiotics available for the treatment of bacterial infections, very few agents have been developed to treat viral diseases. Ribavirin (Virazole) is a triazole nucleoside antiviral agent that produces selective antiviral effects against a broad spectrum of RNA and DNA viruses.
openaire +2 more sources
Despite the plethora of antibiotics available for the treatment of bacterial infections, very few agents have been developed to treat viral diseases. Ribavirin (Virazole) is a triazole nucleoside antiviral agent that produces selective antiviral effects against a broad spectrum of RNA and DNA viruses.
openaire +2 more sources
Ribavirin Aerosol in the Elderly
Chest, 1988Ribavirin aerosol is effective in treating respiratory syncytial virus and influenzal infections in children and young adults. It has not been studied in elderly patients. We evaluated the safety of ribavirin aerosol in eight elderly volunteers at high risk for influenza.
Howard P. Liss, Jack M. Bernstein
openaire +3 more sources
PHOTOLABELING PROBES OF RIBAVIRIN AND EICAR [PDF]
Nucleosides, Nucleotides & Nucleic Acids, 2005 Ribavirin, the only small molecule available so far for treating hepatitis C virus infection, was recently used in an emergency context to treat patients with severe acute respiratory syndrome in the early stages of the disease. EICAR, one of the most potent congeners of ribavirin, has 10 to 100 times greater antiviral potency than ribavirin.
Jinqiao Wan +5 more
openaire +2 more sources
Nucleosides, Nucleotides and Nucleic Acids, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Stewart W. Schneller, Meral Tuncbilek
openaire +4 more sources
AbstractFor Abstract see ChemInform Abstract in Full Text.
Stewart W. Schneller, Meral Tuncbilek
openaire +4 more sources
Acta Crystallographica Section A Foundations and Advances, 2022
Exhaustive characterisation of polymorphism and phase transitions in active pharmaceutical ingredients (APIs) is of critical importance to pharmaceutical companies in the development of ‘solid forms’ used in patient therapy. Polymorphs of the same API may differ in their physical properties e.g.
Tiwari, B., Giordano, N.
openaire +2 more sources
Exhaustive characterisation of polymorphism and phase transitions in active pharmaceutical ingredients (APIs) is of critical importance to pharmaceutical companies in the development of ‘solid forms’ used in patient therapy. Polymorphs of the same API may differ in their physical properties e.g.
Tiwari, B., Giordano, N.
openaire +2 more sources
Pediatrics, 1988
To the Editor.— The report by McMillan and colleagues1 of the nonpredictiveness of certain clinical and laboratory tests in determining the duration of hospitalization of patients with respiratory syncytial virus adds to our understanding of this important respiratory pathogen.
B, Dashefsky, E R, Wald, M, Green
openaire +2 more sources
To the Editor.— The report by McMillan and colleagues1 of the nonpredictiveness of certain clinical and laboratory tests in determining the duration of hospitalization of patients with respiratory syncytial virus adds to our understanding of this important respiratory pathogen.
B, Dashefsky, E R, Wald, M, Green
openaire +2 more sources
Effects of Ribavirin on Neutrophil Function
The American Journal of the Medical Sciences, 1988Ribavirin, a broad spectrum antiviral agent, has been shown to exhibit immunosuppressive activity. This property has raised concerns during clinical trials because candidates for antiviral therapy are those who may develop secondary bacterial infection.
Steele, Russell W. +4 more
openaire +4 more sources
Infection Control, 1987
AbstractThe recent approval of ribavirin aerosol for the treatment of severe respiratory syncytial virus (RSV) in infants and young children is a significant addition to the antiviral drugs available today. When administered as an aerosolized form by face mask or mist tent for 20 to 21 hours per day, ribavirin effectively decreases the symptoms of RSV ...
openaire +2 more sources
AbstractThe recent approval of ribavirin aerosol for the treatment of severe respiratory syncytial virus (RSV) in infants and young children is a significant addition to the antiviral drugs available today. When administered as an aerosolized form by face mask or mist tent for 20 to 21 hours per day, ribavirin effectively decreases the symptoms of RSV ...
openaire +2 more sources