Results 241 to 250 of about 74,231 (262)
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Photoallergic Skin Reaction To Ribavirin
American Journal of Gastroenterology, 1999A 65-yr-old woman with chronic hepatitis C was treated with three million units interferon-alpha t.i.w. and 1000 mg ribavirin daily. At wk 16 of combination therapy the patient developed an itchy eczematous erythema, partly of urticarial character, which was almost confined to ultraviolet (UV)-exposed sites.
D. Stryjek-Kaminska +4 more
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Blood, 2006
Abstract Ribavirin is a synthetic nucleoside analogue given with pegylated interferon alfa-2a for the treatment of hepatitis C. Hemolytic anemia has been reported in 10–15% of patients, usually within 1–2 weeks of the initiation of therapy. The pathogenesis of this phenomenon is unclear.
Reema Batra +3 more
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Abstract Ribavirin is a synthetic nucleoside analogue given with pegylated interferon alfa-2a for the treatment of hepatitis C. Hemolytic anemia has been reported in 10–15% of patients, usually within 1–2 weeks of the initiation of therapy. The pathogenesis of this phenomenon is unclear.
Reema Batra +3 more
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Marked elevation of erythrocyte ribavirin levels in interferon and ribavirin-induced anemia
Clinical Gastroenterology and Hepatology, 2004To elucidate the effects of blood ribavirin disposition on ribavirin-induced anemia, the relationship between erythrocyte ribavirin concentration and change in hematologic parameters was examined in interferon and ribavirin combination therapy for HCV eradication.Nine HCV RNA-positive patients were treated with combination therapy including 11.3 +/- 1 ...
Yasushi Matsuzaki +6 more
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Ribavirin Aerosol Treatment of Influenza
Infectious Disease Clinics of North America, 1987In this article we have described the clinical and laboratory features of uncomplicated influenza in college students and its treatment with ribavirin aerosol. The disease presents as an acute febrile systemic illness of short duration that varies little from patient to patient. Peripheral blood cell changes in the infection are also quite specific and
Brian E. Gilbert, Vernon Knight
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Assessing Ribavirin Exposure During Pregnancy
Gastroenterology Nursing, 2008Ribavirin, used in combination with an interferon, is used for the treatment of chronic hepatitis C. Ribavirin is a Federal Drug Administration Pregnancy Category X product, indicating that its use is contraindicated in women who are pregnant. The package insert also states that ribavirin is contraindicated in men whose partners may become pregnant ...
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Ribavirin response in measles pneumonia
Journal of Infection, 1990A 9-year-old boy with Hodgkin's disease developed measles 1 month after completing eight courses of intensive anti-cancer chemotherapy. The atypical nature of the rash and the absence of Koplik's spots indicated a high risk of progression to fatal giant cell pneumonia.
Richard F. Stevens +2 more
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Peginterferon plus ribavirin versus interferon plus ribavirin for chronic hepatitis C
Cochrane Database of Systematic Reviews, 2014Pegylated interferon (peginterferon) plus ribavirin is the recommended treatment for patients with chronic hepatitis C, but systematic assessment of the effect of this treatment compared with interferon plus ribavirin is needed.To systematically evaluate the benefits and harms of peginterferon plus ribavirin versus interferon plus ribavirin for ...
Hauser, Goran +7 more
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Peginterferon-α2b and ribavirin
Expert Review of Anti-infective Therapy, 2004Hepatitis C virus infection is among the leading causes of chronic liver disease in the USA and has a worldwide prevalence of approximately 300 million people. Chronic hepatitis C virus is the most common indication for liver transplantation in the USA.
Steven L. Flamm, Joseph Ahn
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Metabolism and antiviral activity of ribavirin
Virus Research, 2005Thirty years after its synthesis, the mechanism of action of ribavirin is still not completely understood. Although much is known about the metabolism and biochemical effects of ribavirin in human cells, there is still much to be learned about the precise mechanism of action of ribavirin with the various viruses.
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