Results 281 to 290 of about 156,401 (384)

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

open access: yesAdvanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu   +9 more
wiley   +1 more source

Built differently or defective: can RNA exosomopathies cause ribosome heterogeneity? [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci
Bressman ZJ, Corbett AH, Ghalei H.
europepmc   +1 more source

Ribonuclease activity and RNA binding of recombinant human Dicer

open access: yesEMBO Journal, 2002
P. Provost   +5 more
semanticscholar   +1 more source

Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix

open access: yesAdvanced Science, EarlyView.
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang   +16 more
wiley   +1 more source

A Comparative Overview of the Role of Human Ribonucleases in Nonsense-Mediated mRNA Decay. [PDF]

open access: yesGenes (Basel)
da Costa PJ   +8 more
europepmc   +1 more source

Enzymatic Activity of Polyalanyl Ribonuclease

open access: hybrid, 1963
Daniel Wellner   +2 more
openalex   +1 more source

O‐GalNAc Glycosylation Activates MBL‐Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis

open access: yesAdvanced Science, EarlyView.
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen   +24 more
wiley   +1 more source

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