Results 281 to 290 of about 156,401 (384)
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu+9 more
wiley +1 more source
Built differently or defective: can RNA exosomopathies cause ribosome heterogeneity? [PDF]
Bressman ZJ, Corbett AH, Ghalei H.
europepmc +1 more source
The Specific Alkylation by Iodoacetamide of Histidine-12 in the Active Site of Ribonuclease
Rachel G. Fruchter, Arthur M. Crestfield
openalex +1 more source
Ribonuclease activity and RNA binding of recombinant human Dicer
P. Provost+5 more
semanticscholar +1 more source
Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang+16 more
wiley +1 more source
A Comparative Overview of the Role of Human Ribonucleases in Nonsense-Mediated mRNA Decay. [PDF]
da Costa PJ+8 more
europepmc +1 more source
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen+24 more
wiley +1 more source
Technologies for Targeted RNA Degradation and Induced RNA Decay. [PDF]
Mikutis S, Bernardes GJL.
europepmc +1 more source