Inhibition of human cytomegalovirus major capsid protein expression and replication by ribonuclease P-associated external guide sequences. [PDF]
Deng Q +15 more
europepmc +1 more source
Prediction of terminal protein and ribonuclease H domains in the gene P product of hepadnaviruses [PDF]
Yu.E. Khudyakov, A.M. Makhov
openalex +1 more source
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng +12 more
wiley +1 more source
A screening platform to monitor RNA processing and protein-RNA interactions in ribonuclease P uncovers a small molecule inhibitor. [PDF]
Madrigal-Carrillo EA +4 more
europepmc +1 more source
Interaction of the 3′-end of tRNA with ribonuclease P RNA [PDF]
Bong-Kyeong Oh, Norman R. Pace
openalex +1 more source
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao +5 more
wiley +1 more source
Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P. [PDF]
Klemm BP +9 more
europepmc +1 more source
Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes [PDF]
Magnus Alm Rosenblad +3 more
openalex +1 more source
ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou +8 more
wiley +1 more source

