Results 111 to 120 of about 22,100 (253)
Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii
Advanced Science, EarlyView.The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou +11 more
wiley +1 more source
Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation
Advanced Science, EarlyView.Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu +9 more
wiley +1 more source
Fractionation of Ribonuclease-resistant Fraction on ECTEOLA-cellulose [PDF]
, 1958 Kentaro Tanaka
openalex +1 more source
DNA Molecular Computing with Weighted Signal Amplification for Cancer miRNA Biomarker Diagnostics
Advanced Science, EarlyView.A molecular computing approach is presented with weighted signal amplification. Polymerase‐mediated strand displacement is employed to assign weights to target miRNAs, reflecting the miRNAs’ diagnostic values, followed by amplification of the weighted signals using localized DNA catalytic hairpin assembly.
Hongyang Zhao +6 more
wiley +1 more source
An Engineered PfAgo with Wide Catalytic Temperature Range and Substrate Spectrum
Advanced Science, EarlyView.This work presents a strategy for engineering thermophilic Ago proteins to obtain wide catalytic temperature range and broad substrate spectrum. This strategy is applied to engineer PfAgo and TtdAgo, and the biochemical properties of the engineered PfAgo are systematically characterized. The study further elucidates the structural differences involved.
Longyu Wang +11 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that the miRNA pathway plays a key role in the invasive growth of Alternanthera philoxeroides in aquatic habitats. Specifically, miR162 is critical for its invasive success, facilitating stem elongation and enhancing survival during submergence.
Qianqian Hu +8 more
wiley +1 more source
MOLECULAR WEIGHT AND ELECTROPHORESIS OF CRYSTALLINE RIBONUCLEASE [PDF]
, 1940 Alexandre Rothen
openalex +1 more source
Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair
Advanced Science, EarlyView.CircGLIS3(2), a circRNA transiently upregulated in dermal fibroblasts during acute wound healing, is induced by IL‐1α and TGF‐β. Its RNA activates fibroblasts into matrix‐secreting cells, while its encoded protein enhances proliferation. The RNA stabilizes PCOLCE, and the protein interacts with BTF3, collectively accelerating wound repair. Abstract The
Guanglin Niu +20 more
wiley +1 more source