Results 111 to 120 of about 121,107 (346)
Approaches to repurposing reverse transcriptase antivirals in cancer
British Journal of Clinical Pharmacology, EarlyView.This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head +2 more
wiley +1 more source
RNA-binding protein immunoprecipitation as a tool to investigate plant miRNA processing interference by regulatory proteins of diverse origin [PDF]
, 2018 Background: Due to the nature of viral RNA genomes, RNA viruses depend on many RNA-binding proteins (RBP) of viral and host origin for replication, dissemination and evasion of host RNA degradation pathways.
Garcia, Maria Laura +2 more
core +2 more sources
Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition
BioEssays, EarlyView.Annexins are an important protein family traditionally well known to bind to phospholipids and to interact with various proteins in a calcium dependent way. More recently, it has been established that a feature common to the family is also to bind to RNA having a role in translation. In bies70019 article, Vedeler et al.
Anni Vedeler +2 more
wiley +1 more source
A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome [PDF]
, 2013 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Dunker, A. Keith +6 more
core +2 more sources
Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer
BioEssays, EarlyView.Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2020 Shengjie Tang, Weifen Zhu, Fenping Zheng, Weiwei Gui, Wenjing Zhang, Xihua Lin, Hong Li Department of Endocrinology, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou 310016, Zhejiang, People’s Republic of ...
Tang S +6 more
doaj
In vivo and in vitro models of demyelinating diseases. V. Comparison of the assembly of mouse hepatitis virus, strain JHM, in two murine cell lines. [PDF]
, 1982 The developmental sequence of a neurotropic strain (JHM) of mouse hepatitis virus was examined by transmission electron microscopy and immunocytology. The nucleoprotein core of this coronavirus, which contains RNA of positive polarity and is helical in ...
Buchmeier, MJ +4 more
core
There is no correlation between c-Myc mRNA expression and telomerase activity in human breast cancer [PDF]
, 2004 Background Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal length and stability thus leading to cellular immortalisation.
Kirkpatrick, KL, Mokbel, K, Newbold, RF
core +2 more sources
Biotechnology and Bioengineering, EarlyView.A novel strategy for nuclear gene delivery in microalgae using a cell‐penetrating peptide (CPP) and nuclear localization signal (NLS) is described. The authors developed a triple nanocomplex of CPP, plasmid DNA, and SV40 NLS to enhance nuclear delivery in Chlamydomonas reinhardtii.
Eun Jeong Sim +10 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 2001 We used the interaction of Hop stunt viroid (HSVd) and cucumber plants to investigate the involvement of phloem proteins in the systemic transport of RNA molecules.
Gustavo Gómez, Vicente Pallás
doaj +1 more source