Results 141 to 150 of about 121,107 (346)
International Journal of Cancer, EarlyView.Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li +7 more
wiley +1 more source
CRISPR/Cas9 Knockout of Shell Matrix Protein 1 in the Slipper‐Snail Crepidula atrasolea
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.Methods for CRISPR/Cas9 shell matrix protein knockout in the snail, Crepidula atrasolea including optimizing RNP delivery and embryo husbandry, to the use of Sanger and MiSeq sequencing, and high‐content screening of embryos to characterize the loss of Shell Matrix Protein 1 (SMP1) during larval shell development.
Grant Batzel +13 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Osteoarthritis (OA) is a common degenerative osteoarthropathy with an unclear pathogenesis. Circular RNA (circRNA) has been reported to be associated with OA progression. This study aims to explore the role and potential mechanism of hsa_circ_0006646 in OA. Interleukin‐1β (IL‐1β)‐induced human chondrocytes were used as the cell model of OA. RT‐
Ming‐Yu Hua +3 more
wiley +1 more source
Long non-coding RNA SENCR is a positive regulator of ETV2 [PDF]
, 2017 Department of Biological SciencesAlthough long non-coding RNAs (lncRNAs) have emerged as novel regulator of cell fate and gene expression, the regulation of vascular specific transcription factor by lncRNA in generation of induced endothelial cells ...
Jeong, Yujin
core
Regulation of polyribosome formation and protein synthesis in the uterus. Isolation of cytoplasmic ribonucleoprotein particles and the principal properties of the cell-free protein-synthesizing system [PDF]
, 1967 Ching-Sung Teng, Terrell H. Hamilton
openalex +1 more source
Beta cells to brain cells: The pivotal role of insulin and glucose metabolism in Alzheimer's disease
Neuroprotection, EarlyView.Common metabolic, histochemical, and molecular pathologies: Type 2 diabetes and dementia. Abstract The risk factors and neuropathologies of cognitive decline and the onset and progression of dementia‐related disorders were, until recently, obtuse. A critical predisposing factor to Alzheimer's disease (AD) that has emerged is glucose dysmetabolism.
Stanley S. Schwartz +3 more
wiley +1 more source
LABELLING OF IMMUNOLOGICALLY SPECIFIC PROTEINS BY RIBONUCLEOPROTEIN PARTICLES FROM RAT-LIVER AND CHICK-LIVER CELL SAP [PDF]
, 1963 ALEXANDRA VON DER DECKENA
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Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways
PROTEOMICS, EarlyView.ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu +3 more
wiley +1 more source
Formation of Ribosomes from Precursor Ribonucleoprotein Particles [PDF]
, 1965 Paul S. Sypherd
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PLANTS, PEOPLE, PLANET, EarlyView.Viticulture is facing increasing challenges due to climate change. The focus on fast growth and sweet berries has come at the expense of stress resilience. Grafting onto Phylloxera‐resistant rootstocks from American species has been the most successful form of ecological pest management.
Samia Daldoul +6 more
wiley +1 more source