Transgenic resistance to PMTV and PVA provides novel insights to viral long-distance movement [PDF]
The studies in this thesis describe forms of transgenic resistance to plant viruses and how they can be used for studying viral infection cycle. S. tuberosum cv.
Germundsson, Anna
core
Structural organization of the ribonucleoprotein in Escherichia coli [PDF]
Elizabeth Kingsbury, Herbert Voelz
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The Actin‐Binding Prolyl‐Isomerase Par17 Sustains Its Substrate Selectivity by Interdomain Allostery
ABSTRACT The human peptidyl‐prolyl‐cis/trans isomerases (PPIases), Parvulin 14 and Parvulin 17, accelerate the cis/trans isomerization of Xaa‐Pro moieties within protein sequences. By modulating the respective binding interfaces of their target proteins, they play a crucial role in determining the fate of their substrates within the cell. Although both
Anna Sternberg+9 more
wiley +1 more source
Mammalian cells in culture actively export specific microRNAs [PDF]
The discovery of microRNAs (miRNAs) as a new class of regulators of gene expression has triggered an explosion of research, but has left many unanswered questions about how this regulation works and how it is integrated with other regulatory mechanisms ...
David Baxter+4 more
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Cytoplasmic Ribonucleoprotein Components of the Novikoff Hepatoma [PDF]
Edward L. Kuff, Robert F. Zeigel
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ABSTRACT The SARS‐CoV‐2 nucleocapsid protein, or N‐protein, is a structural protein that plays an important role in the SARS‐CoV‐2 life cycle. The N‐protein takes part in the regulation of viral RNA replication and drives highly specific packaging of full‐length genomic RNA prior to virion formation.
Stefan Loonen+3 more
wiley +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa+4 more
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THE FINE STRUCTURE OF THE RIBONUCLEOPROTEIN IN BACTERIAL CYTOPLASM [PDF]
Woutera van Iterson
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Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu+6 more
wiley +1 more source
Incorporation of Amino Acids into Protein in a System Containing Rat Liver Ribonucleoprotein Particles and Chick Liver Cell Sap. [PDF]
Alexandra von der Decken+4 more
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