Dad's legacy: Epigenetic reprogramming and paternal inflammatory memory in offspring health
Abstract Over the past decade, numerous reports have highlighted intergenerational and even transgenerational epigenetic effects resulting from parental exposure to diets, toxins, and stress. In many cases, these parentally induced phenotypes do not seem to confer an obvious benefit, making it challenging to understand the evolutionary drivers behind ...
Shamila D. Alipoor+3 more
wiley +1 more source
Immunofluorescent localization of the proteins of nuclear ribonucleoprotein complexes. [PDF]
Raymond E. Jones+2 more
openalex +1 more source
Orchestrating Neural Development Through mRNA Translation Regulation. [PDF]
Rodrigue B+3 more
europepmc +1 more source
Isolation and visualization of large compact ribonucleoprotein particles of specific nuclear RNAs. [PDF]
P. Spann+3 more
openalex +1 more source
Recent advances in proteomic workflows to interrogate the SUMOylome in plants
Summary Protein posttranslational modifications (PTMs) are vital for regulating protein functions. SUMOylation, a PTM essential for plant survival, involves attaching a Small Ubiquitin‐like MOdifier (SUMO) to lysine residues of target proteins. SUMOylation influences stress tolerance, cell proliferation, protein stability, and gene expression.
Kishor D. Ingole+3 more
wiley +1 more source
CRISPR/Cas9-Based Modeling of <i>JAK2</i> V617F Mutation in K562 Cells Reveals Enhanced Proliferation and Sensitivity to Therapeutic Agents. [PDF]
Nilsri N+4 more
europepmc +1 more source
Molecular cloning of cDNA for the nuclear ribonucleoprotein particle C proteins: a conserved gene family. [PDF]
T Nakagawa+3 more
openalex +1 more source
Summary Alternative splicing is essential for plants, enabling a single gene to produce multiple transcript variants to boost functional diversity and fine‐tune responses to environmental and developmental cues. Arabidopsis thaliana At‐RS31, a plant‐specific splicing factor in the Serine/Arginine‐rich (SR) protein family, responds to light and the ...
Tino Köster+18 more
wiley +1 more source
In Utero Alcohol and Unsuitable Home Environmental Exposure Combined with <i>FMR1</i> Full Mutation Allele Cause Severe Fragile X Syndrome Phenotypes. [PDF]
Winarni TI+9 more
europepmc +1 more source