Results 241 to 250 of about 144,340 (386)

Gesicle-Mediated Delivery of CRISPR/Cas9 Ribonucleoprotein Complex for Inactivating the HIV Provirus.

Molecular Therapy, 2019
Lee A. Campbell, Lamarque Coke, Christopher T. Richie, Lowella V. Fortuno, Aaron Y Park, B. Harvey   +5 more
semanticscholar   +1 more source

Strand displacement‐driven CRISPR/Cas12a framework enables precise identification of low‐abundance point mutations

VIEW, EarlyView.
We established an engineered CRISPR/Cas12a point mutation detection strategy (E‐CRISPR) for low‐abundance point mutations detection. By integrating the precise regulatory mechanism of strand displacement reaction (SDR) with the local high‐concentration probe microenvironment created by tetrahedral DNA frameworks (TDFs), it has achieved simultaneous ...
Jiaxi Mo, Yan Zhao, Chenyu Sun, Mingtao Li, Hengyi Chen, Yufang Zhang, Xiaohui Chen, Xinlin Guo, Zhizeng Wang, Yonghong Wang, Jichun Yang, Yang Luo   +11 more
wiley   +1 more source

Unmasking Cryoglobulinemia: A Cold-Blooded Complication of Hepatitis C. [PDF]

Case Reports Hepatol
Arges AM, Levine A.
europepmc   +1 more source

Isolation and characterization of a complementary DNA expressing human U1 small nuclear ribonucleoprotein C polypeptide. [PDF]

, 1988
Katsuya Yamamoto, Hitoshi Miura, Y Möroi, S Yoshinoya, Masahide Goto, Kenichi Nishioka, Tomofumi Miyamoto   +6 more
openalex   +1 more source

Role of mitochondrial complex I genes in host plant expansion of Bactrocera tau (Tephritidae: Diptera) by CRISPR/Cas9 system

Insect Science, EarlyView.
The role of 3 mitochondrial complex I gene in host expansion of Bactrocera tau was verified by CRISPR/Cas9 gene editing system. A stable homogenous strain (Btndufa7‐/‐) of B.tau was established after silencing Ndufa7. The reduced size of larvae and pupae of Ndufa7 knockout strain was first found.Then different levels of fitness and relative expression ...
Wei Shi, Linsheng He, Ruixiang Li, Jun Cao   +3 more
wiley   +1 more source

Increased expression of chaperone proteins in response to DENV 2 infection of Huh-7 liver cells. [PDF]

PLoS One
Chumchanchira C, Sornjai W, Roytrakul S, Lithanatudom P, Smith DR.   +4 more
europepmc   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source

Small RNA in sperm-Paternal contributions to human embryo development. [PDF]

Nat Commun
Isacson S, Karlsson K, Zalavary S, Asratian A, Kugelberg U, Liffner S, Öst A.   +6 more
europepmc   +1 more source

Different parts of the mussel Gigantidas haimaensis holobiont responded differently to deep‐sea sampling stress

Integrative Zoology, EarlyView.
Symbiotic gill and nonsymbiotic mantle of mussel Gigantidas haimaensis responded differently to deep‐sea sampling stress caused by acute environmental changes. Sharply increased transcription factors potentially play key roles in initiating the response of sampled deep‐sea macrobenthos to the sampling stress.
Guoyong YAN, Tong WEI, Yi LAN, Ting XU, Peiyuan QIAN   +4 more
wiley   +1 more source

Have we really solved rAAV6 toxicity? A closer look at mannose-coupled rAAV6 vectors. [PDF]

Mol Ther Nucleic Acids
Klatt D, Brendel C.
europepmc   +1 more source