Results 261 to 270 of about 144,340 (386)

Compartmentalisation in cAMP signalling: A phase separation perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Proteomics of the temporal cortex in semantic dementia reveals brain-region specific molecular pathology and regulation of the TDP-43-ANXA11 interactome. [PDF]

open access: yesActa Neuropathol Commun
Miedema SSM   +11 more
europepmc   +1 more source

TP‐0903 Suppresses Aurora A–PLK1 Signaling to Inhibit Proliferation of a Myelodysplastic Syndrome‐Derived Cell Line

open access: yesCancer Science, EarlyView.
TP‐0903 exerts the antitumor effects through diverse cell‐specific mechanisms, including apoptosis, ferroptosis, and cell cycle disruption. These insights underline the potential of TP‐0903 as a therapeutic agent for hematological malignancies and emphasize the need for further research to fully elucidate the molecular targets of TP‐0903 and optimize ...
Tomoko Kimura‐Hyoda   +10 more
wiley   +1 more source

Efficient genome editing in Fusarium oxysporum based on CRISPR/Cas9 ribonucleoprotein complexes.

open access: yesFungal Genetics and Biology, 2018
Qiang Wang   +2 more
semanticscholar   +1 more source

CircCDYL Association With hnRNPL Modulates CDYL Isoform Switching in Breast Cancer Cells

open access: yesCancer Science, EarlyView.
We investigated the synergic role of the circRNA circCDYL and the splicing factor hnRNPL in modulating alternative splicing and isoform switch in breast cancer cells, with a focus on circCDYL and hnRNPL‐mediated isoform switch events involving the CDYL gene.
Serena Bernardi   +11 more
wiley   +1 more source

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