Results 291 to 300 of about 144,340 (386)

A ribonucleoprotein octamer for targeted siRNA delivery

Nature Biomedical Engineering, 2018
Wanyi Tai, Junwei Li, E. Corey, Xiaohu Gao   +3 more
semanticscholar   +1 more source

TSC22D1 is a newly identified inhibitor of insulin secretion in pancreatic beta cells

The FEBS Journal, EarlyView.
TSC22D1 acts downstream of glucose signaling and negatively regulates insulin secretion in pancreatic beta cells. Mechanistically, TSC22D1 interacts with FoxO1. Elevated glucose levels enhance the TSC22D1–FoxO1 interaction indirectly by increasing the protein abundance of TSC22D1. Importantly, TSC22D1 and FoxO1 not only physically associate but also co‐
Sümbül Yıldırım, Amit Mhamane, Svenja Lösch, Annika Wieder, Ezgi Ermis, Ann‐Christine König, Sevgican Yilmaz, Stefanie M. Hauck, Fatih Kocabas, Julia Szendroedi, Stephan Herzig, Bilgen Ekim   +11 more
wiley   +1 more source

Multiple malignancy-associated dermatomyositis myositis-specific autoantibodies in dermatomyositis. [PDF]

JAAD Case Rep
Choi J, Mir A, Wu B.
europepmc   +1 more source

Ribonucleoprotein of Avian Infectious Bronchitis Virus

, 1981
Heather A. Davies, R. R. Dourmashkin, M. R. Macnaughton   +2 more
openalex   +1 more source

Genome editing via delivery of Cas9 ribonucleoprotein.

Methods, 2017
M. DeWitt, J. Corn, D. Carroll
semanticscholar   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

Mechanism of expression regulation of head-to-head overlapping protein-coding genes INO80E and HIRIP3. [PDF]

Commun Biol
Ryczek N, Łyś A, Wanowska E, Kozłowska-Masłoń J, Makałowska I.   +4 more
europepmc   +1 more source

The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins.

, 1988
Jeffrey R. Patton, Thoru Pederson
openalex   +1 more source

SYNCAS‐mediated CRISPR‐Cas9 genome editing in the Jewel wasp, Nasonia vitripennis

Insect Molecular Biology, EarlyView.
Maternal injection of Cas9 RNP together with BAPC and saponins (SYNCAS) results in efficient gene editing of Nasonia vitripennis offspring. The timing of injection and egg collection is important for maximising efficiency and reducing screening effort.
Filippo Guerra, Sander De Rouck, Eveline C. Verhulst   +2 more
wiley   +1 more source

In Utero Alcohol and Unsuitable Home Environmental Exposure Combined with <i>FMR1</i> Full Mutation Allele Cause Severe Fragile X Syndrome Phenotypes. [PDF]

Int J Mol Sci
Winarni TI, Aishworiya R, Culpepper H, Zafarullah M, Mendoza G, Wilaisakditipakorn TJ, Likhitweerawong N, Law J, Hagerman R, Tassone F.   +9 more
europepmc   +1 more source