Results 291 to 300 of about 121,107 (346)

Analysis of Treatment and Subsequent Pregnancy Outcomes in Patients With Antinuclear Antibody‐Positive Recurrent Spontaneous Abortion

Immunity, Inflammation and Disease, Volume 13, Issue 6, June 2025.
ABSTRACT Background The etiology of recurrent spontaneous abortion (RSA) has not been clearly defined. The role of autoantibodies in RSA has particularly attracted much attention. Objective A retrospective analysis was performed to explore the combinatory efficacy of five drugs (aspirin enteric‐coated tablets, hydroxychloroquine sulfate ...
Ancong Wang, Fengxia Wu, Min Liu, Zhenchun Zhang, Shuxia Li, Qihua Tan   +5 more
wiley   +1 more source

Optimization and Benchmarking of RT-LAMP-CRISPR-Cas12a for the Detection of SARS-CoV-2 in Saliva. [PDF]

Int J Mol Sci
Lynch CRH, Drummond RSM, Jelley L, Baker L, Smit E, Fleming R, Billington C.   +6 more
europepmc   +1 more source

Engineering of CD63 Enables Selective Extracellular Vesicle Cargo Loading and Enhanced Payload Delivery

Journal of Extracellular Vesicles, Volume 14, Issue 6, June 2025.
ABSTRACT Extracellular vesicles (EVs) are mediators of intercellular communication through the transfer of nucleic acids, lipids and proteins between cells. This property makes bioengineered EVs promising therapeutic vectors. However, it remains challenging to isolate EVs with a therapeutic payload due to the heterogeneous nature of cargo loading into ...
Wataru Obuchi, Ayrton Zargani‐Piccardi, Kevin Leandro, David Rufino‐Ramos, Emilio Di lanni, Dawn Madison Frederick, Katia Maalouf, Lisa Nieland, Tianhe Xiao, Pierre Repiton, Christine A. Vaine, Benjamin P. Kleinstiver, D. Cristopher Bragg, Hakho Lee, Miles A. Miller, Xandra O. Breakefield, Koen Breyne   +16 more
wiley   +1 more source

Stress granules: emerging players in neurodegenerative diseases. [PDF]

Transl Neurodegener
Yuan L, Mao LH, Huang YY, Outeiro TF, Li W, Vieira TCRG, Li JY.   +6 more
europepmc   +1 more source

m6A-related genes and their role in Parkinson's disease: Insights from machine learning and consensus clustering. [PDF]

Medicine (Baltimore)
Yan J, Wang Z, Li Y, Li R, Xiang K.
europepmc   +1 more source

New Mechanisms and Therapeutic Targets in Systemic Lupus Erythematosus

MedComm, Volume 6, Issue 6, June 2025.
Systemic lupus erythematosus (SLE) is a multiple organ involved autoimmune disorder with heterogeneous clinical manifestations. Despite hallmark features such as elevated type I interferon and the production of numerous autoantibodies, the underlying pathogenic mechanisms remain elusive.
Jingru Tian, Hang Zhou, Wei Li, Xu Yao, Qianjin Lu   +4 more
wiley   +1 more source

A Case of Systemic Lupus Erythematosus With Sole Anti-phosphatidylserine/Prothrombin Complex Antibodies Complicated by Vertebral Artery Dissection. [PDF]

Cureus
Shimizu H, Nishioka H.
europepmc   +1 more source

Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang, Minqiao Lu, Yi Zhang, Jiangwen Ma, Ying Hu   +4 more
wiley   +1 more source

Rapid and robust validation of pooled CRISPR knockout screens using CelFi. [PDF]

Sci Rep
Loughran AJ, Narina S, Klein J, Siwak JF, Connelly JP, Pruett-Miller SM.   +5 more
europepmc   +1 more source

Immune Thrombocytopenia in an Adult With X-linked Agammaglobulinemia: A Case Report. [PDF]

EJHaem
Matsunaga T, Naganuma K, Tanabe N, Mori Y, Nagata M, Momose S, Kubota Y.   +6 more
europepmc   +1 more source