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RNAs and ribonucleoproteins in recognition and catalysis [PDF]

European Journal of Biochemistry, 1994
CONTENTS. 1. Did life begin with catalytic RNA?–2. Self‐splicing and self‐cleaving RNAs–2.1 Self‐splicing of group I introns – 2.2 Self‐splicing of group II introns – 2.3 Self‐cleaving RNAs–3. Splicing mediated by trans‐acting factors–3.1 Group III introns – 3.2 Splicing of nuclear pre‐mRNAs – 3.3 Trans‐splicing – 3.4 Is nuclear pre‐mRNA splicing ...
Tom H. Wittop Koning, Daniel Schümperli
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Autoantibodies to Ribonucleoproteins

Clinics in Rheumatic Diseases, 1985
Presently we recognize at least 12 different autoantibodies that involve ribonucleoproteins as antigens in patients with SLE and other rheumatic diseases. Such autoantibodies have a number of clinically useful diagnostic associations. Moreover, they have proved to be powerful tools for understanding the structure and function of a variety of cellular ...
Tsuneyo Mimori, John A. Hardin
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Antibodies in Ribonucleoproteins

Nature, 1960
IN many hypotheses concerning the mechanism of the immune response the nucleic acids have been assigned a role in the production of antibodies, although no clear evidence for their participation is yet available. As regards protein synthesis in general, there is reason for believing that the ribonucleoproteins lie in the pathway of this synthetic ...
Michael Feldman, Elson D, Globerson A
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The SMN complex, an assemblyosome of ribonucleoproteins

Current Opinion in Cell Biology, 2002
Spinal muscular atrophy is a common, often lethal, neurodegenerative disease that results from low levels of, or loss-of-function mutations in, the SMN (survival of motor neurons) protein. SMN oligomerizes and forms a stable complex with five additional proteins: Gemins 2-6. SMN also interacts with several additional proteins referred to as "substrates"
Paushkin, Sergey, Gubitz, Amélie, Massenet, Séverine, Dreyfuss, Gideon   +3 more
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Small nuclear ribonucleoprotein antigens are absent from 10S translation inhibitory ribonucleoprotein but present in cytoplasmic messenger ribonucleoprotein and polysomes

Archives of Biochemistry and Biophysics, 1986
A cytoplasmic 10S ribonucleoprotein particle (iRNP), which is isolated from chick embryonic muscle, is a potent inhibitor of mRNA translation in vitro and contains a 4S translation inhibitory RNA species (iRNA). The iRNP particle shows similarity in size to the small nuclear ribonucleoprotein (snRNP) particles.
Dipak Chakraborty, Dipak Chakraborty, Paul F. Agris, Andra M. Boak, Satyapriya Sarkar, Satyapriya Sarkar, Shirley A. Kovacs   +6 more
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Small Cytoplasmic Ribonucleoproteins

2013
It is now well established that most RNAs are tightly associated with one or more proteins to generate nuclear or cytoplasmic ribonucleoprotein (RNP) complexes. Over 30 years ago, Lerner, Steitz, and coworkers found that the proteic components of these complexes made up some of the antigens recognized by sera of patients affected by systemic lupus ...
ROMANO, MAURIZIO, BURATTI, EMANUELE
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ENZYMATIC DEGRADATION OF RIBONUCLEOPROTEINS

American Journal of Botany, 1951
THE ACTION of crystalline enzymes in degrading cellular substrates of fixed tissues can be determined by suitable staining procedures. Thus, as Brachet (1940) has shown, tissues that have been incubated in ribonuclease and then stained with Unna's combination of methyl green and pyronin show little or no color in cytoplasm and nucleoli, whereas these ...
Berwind P. Kaufmann, Helen Gay, Margaret R. McDonald   +2 more
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Informational ribonucleoprotein particles of newt oocytes: Polyribosome-associated ribonucleoproteins

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1974
Various species of rapidly labelled, informational ribonucleoproteins can be isolated from homogenates of newt oocytes. Polyribosome-associated ribonucleoprotein can be separated from heterogeneous nuclear ribonucleoprotein and free cytoplasmic ribonucleoprotein by sucrose gradient centrifugation.
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Ribonucleoproteins of Uukuniemi virus are circular [PDF]

Journal of Virology, 1975
The internal ribonucleoprotein (RNP) of Uukuniemi virus was released with Triton X-100 and analyzed on sucrose gradients. Three species of RNP sedimenting at 140 to 150, 105 to 120, and 85 to 90S could be separated. All of them contained the same ratio of core polypeptide (mol wt, 25,000) to RNA. Eelctron microscopy using rotatory shadowing showed that
C H von Bonsdorff, Ralf F. Pettersson
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The Phlebovirus Ribonucleoprotein: An Overview

In negative strand RNA viruses, ribonucleoproteins, not naked RNA, constitute the template used by the large protein endowed with polymerase activity for replicating and transcribing the viral genome. Here we give an overview of the structures and functions of the ribonucleoprotein from phleboviruses.
Ferron, François, Lescar, Julien
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