Results 61 to 70 of about 144,340 (386)

Autoantibodies to heterogeneous nuclear ribonucleoproteins

Autoimmunity, 2005
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are among the most abundant proteins in the eukaryotic cell nucleus and play a direct role in several aspects of the RNA life including splicing, export of the mature RNAs and translation. To date, approximately 30 proteins have been identified.
CAPORALI R., BUGATTI S., BRUSCHI E., CAVAGNA L., MONTECUCCO C.   +4 more
openaire   +3 more sources

Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing

eLife, 2016
Polypyrimidine-tract binding protein PTBP1 can repress splicing during the exon definition phase of spliceosome assembly, but the assembly steps leading to an exon definition complex (EDC) and how PTBP1 might modulate them are not clear.
Somsakul Pop Wongpalee, Ajay Vashisht, Shalini Sharma, Darryl Chui, James A Wohlschlegel, Douglas L Black   +5 more
doaj   +1 more source

MAFG-AS1 is a prognostic biomarker and facilitates prostate cancer progression

Frontiers in Oncology, 2022
Long Noncoding RNAs (LncRNAs) have recently been identified as key regulator in tumor progression. The LncRNA MAFG-AS1 has been reported to facilitate the progression of multiple cancers, however, its role in prostate cancer is still unknown.
Peizhang Li, Yuanping Shi, Miaomiao Guo, Miaomiao Guo, Huan Xu, Ming Zhan, Zhong Wang, Yanbo Chen   +7 more
doaj   +1 more source

eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts [PDF]

, 2016
Background: We have previously shown that the eukaryotic elongation factor subunit 1B gamma (eEF1Bγ) interacts with the RNA polymerase II (pol II) alpha-like subunit “C” (POLR2C), alone or complexed, in the pol II enzyme. Moreover, we demonstrated that
Ammassari-teule, Martine, Borreca, Antonella, Corbi, Nicoletta, DELLE MONACHE, Francesca, Di Certo, Maria Grazia, Fanciulli, Maurizio, Gabanella, Francesca, Onori, Annalisa, Passananti, Claudio, Pisani, Cinzia   +9 more
core   +1 more source

Interplay Between Short-range Attraction and Long-range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein-RNA Complexes

bioRxiv, 2019
In eukaryotic cells, ribonucleoproteins (RNPs) form mesoscale condensates by liquid-liquid phase separation that play essential roles in subcellular dynamic compartmentalization.
Ibraheem Alshareedah, Taranpreet Kaur, Jason A. Ngo, Hannah Seppala, Liz-Audrey Djomnang Kounatse, Wen Wang, M. M. Moosa, Priya R Banerjee   +7 more
semanticscholar   +1 more source

Dissection of affinity captured LINE-1 macromolecular complexes

eLife, 2018
Long Interspersed Nuclear Element-1 (LINE-1, L1) is a mobile genetic element active in human genomes. L1-encoded ORF1 and ORF2 proteins bind L1 RNAs, forming ribonucleoproteins (RNPs).
Martin S Taylor, Ilya Altukhov, Kelly R Molloy, Paolo Mita, Hua Jiang, Emily M Adney, Aleksandra Wudzinska, Sana Badri, Dmitry Ischenko, George Eng, Kathleen H Burns, David Fenyö, Brian T Chait, Dmitry Alexeev, Michael P Rout, Jef D Boeke, John LaCava   +16 more
doaj   +1 more source

Influenza A nucleoprotein binding sites for antivirals: current research and future potential [PDF]

, 2014
This document is the Accepted Manuscript version of the following article: Andreas Kukol and Hershna Patel, ‘Influenza A nucleoprotein binding sites for antivirals: current research and future potential’, Future Biology, Vol 9(7): 625-627, July 2014. The
Kukol, A, Kukol, A, Patel, H., Patel, H.
core   +2 more sources

Enhanced Ribonucleoprotein Immunoprecipitation (RIP) Technique for the Identification of mRNA Species in Ribonucleoprotein Complexes

Bio-Protocol, 2022
RNA binding proteins (RBPs) are critical regulators of cellular phenotypes, and dysregulated RBP expression is implicated in various diseases including cancer.
Saja Fakhraldeen, Scott Berry, David Beebe, Caroline Alexander   +3 more
doaj   +1 more source

Protein or ribonucleoprotein-mediated blocking of recombinase polymerase amplification enables the discrimination of nucleotide and epigenetic differences between cell populations

Communications Biology, 2021
Fujita et al. investigate the use of oligoribonucleotides, proteins, and ribonucleoprotein complexes as sequence-specific blockers of DNA extension by DNA polymerases.
Toshitsugu Fujita, Shoko Nagata, Hodaka Fujii   +2 more
doaj   +1 more source

Analysis of the extranucleolar ribonucleoprotein particles of Cycas revoluta Thunb. (Cycadaceae) and Ceratozamia mexicana Brongn. (Zamiaceae)

Botan‪ical Sciences, 2022
Background: Nuclear ribonucleoprotein particles play a key role in RNA processing and in the gene expression pathway. Interchromatin granules (GICs) involved in the metabolism of pre-messenger RNA (pre-mRNA) were described in Allium cepa and ...
Lourdes-Teresa Agredano-Moreno, María de Lourdes Segura-Valdez, Jaime Jiménez-Ramírez, Luis-Felipe Jiménez-García   +3 more
doaj   +1 more source