Results 111 to 120 of about 26,264 (280)

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

INTRACELLULAR Leishmania amazonensis KILLING INDUCED BY THE GUANINE NUCLEOSIDE 8-BROMOGUANOSINE

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1998
In this study we investigated the effect of 8-Bromoguanosine, an immunostimulatory compound, on the cytotoxicity of macrophages against Leishmania amazonensis in an in vitro system. The results showed that macrophages treated with 8-Bromoguanosine before
GIORGIO Selma, BARÃO Sandra C.
doaj  

1H-1,2,3-triazolyl-1,6-naphthyridin-7(6H)-ones as Potential Fluorescent Nucleoside Analogues: Synthesis and Optical Properties

open access: yesMolecules
In this article, we present the synthesis and the optical properties of three original molecules as potential fluorescent ribonucleoside analogues incorporating a 1,6-naphthyridin-7(6H)-one scaffold as a fluorescent nucleobase and a 1,2,3-triazole as a ...
Anissa Beghennou   +3 more
doaj   +1 more source

Short, synthetic and selectively 13C-labeled RNA sequences for the NMR structure determination of protein-RNA complexes [PDF]

open access: yes, 2017
We report an optimized synthesis of all canonical 2′-O-TOM protected ribonucleoside phosphoramidites and solid supports containing [13C5]-labeled ribose moieties, their sequence-specific introduction into very short RNA sequences and their use for the ...
Allain, Frédéric H.-T   +4 more
core  

tRNA epitranscriptomics and biased codon are linked to proteome expression in Plasmodium falciparum

open access: yesMolecular Systems Biology, 2018
Among components of the translational machinery, ribonucleoside modifications on tRNAs are emerging as critical regulators of cell physiology and stress response. Here, we demonstrate highly coordinated behavior of the repertoire of tRNA modifications of
Chee Sheng Ng   +8 more
doaj   +1 more source

The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2018
Uncontrolled host immunological reactions directed against tissue-trapped eggs precipitate a potentially lethal, pathological cascade responsible for schistosomiasis.
Kathrin K. Geyer   +8 more
doaj  

Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability

open access: yesNature Communications
Tumor cells must rewire nucleotide synthesis to satisfy the demands of unbridled proliferation. Meanwhile, they exhibit augmented reactive oxygen species (ROS) production which paradoxically damages DNA and free deoxy-ribonucleoside triphosphates (dNTPs).
Minhui Ye   +14 more
doaj   +1 more source

Effect of Alkali on Ribonucleoside 2',3'-monophosphates. [PDF]

open access: bronze, 1968
J. Ahonen   +5 more
openalex   +1 more source

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